Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolite as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-beta-D-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasine.
Narciclasine-4-o-beta-d-glucopyranoside, A Glucosyloxy Amidic Phenanthridone Derivative From Pancratium-maritimum / A. H., Aboudonia; A., Degiulio; Evidente, Antonio; M., Gaber; A. A., Habib; Lanzetta, Rosa; A. A., S.. - In: PHYTOCHEMISTRY. - ISSN 0031-9422. - STAMPA. - 30:(1991), pp. 3445-3448. [10.1016/0031-9422(91)83226-B]
Narciclasine-4-o-beta-d-glucopyranoside, A Glucosyloxy Amidic Phenanthridone Derivative From Pancratium-maritimum
EVIDENTE, ANTONIO;LANZETTA, ROSA;
1991
Abstract
Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolite as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-beta-D-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasine.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
