Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very high yields with complete regio-and good diastereoselectivity. (C) 1997 Elsevier Science Ltd.
Selenium-directed conjugate addition of amines to dimethyl 2-phenylseleno fumarate: Regio and diastereoselective synthesis of 2-phenylseleno-3-amino succinates / M., Bella; F., Donofrio; R., Margarita; L., Parlanti; G., Piancatelli; Mangoni, Alfonso. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 38:(1997), pp. 7917-7918. [10.1016/S0040-4039(97)10046-6]
Selenium-directed conjugate addition of amines to dimethyl 2-phenylseleno fumarate: Regio and diastereoselective synthesis of 2-phenylseleno-3-amino succinates
MANGONI, ALFONSO
1997
Abstract
Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very high yields with complete regio-and good diastereoselectivity. (C) 1997 Elsevier Science Ltd.File in questo prodotto:
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