We have synthesized three peptides corresponding to the N-terminal region of CXCL11 but with different aromatic amino acids, analyzed their conformtions by CD, NMR and MD, simulated their complexes with CXCR3 by docking methods and validated these data by in vitro studies

The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis and binding studies / Palladino, P.; Portella, L.; Colonna, G.; Raucci, R.; Saviano, G.; Rossi, Filomena; Napolitano, M.; Scala, S.; Castello, G.; Costantini, S.. - In: CHEMICAL BIOLOGY & DRUG DESIGN. - ISSN 1747-0285. - (2012), pp. 1-11. [10.1111/j.1747-0285.2012.01397x]

The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis and binding studies

ROSSI, FILOMENA;
2012

Abstract

We have synthesized three peptides corresponding to the N-terminal region of CXCL11 but with different aromatic amino acids, analyzed their conformtions by CD, NMR and MD, simulated their complexes with CXCR3 by docking methods and validated these data by in vitro studies
2012
The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis and binding studies / Palladino, P.; Portella, L.; Colonna, G.; Raucci, R.; Saviano, G.; Rossi, Filomena; Napolitano, M.; Scala, S.; Castello, G.; Costantini, S.. - In: CHEMICAL BIOLOGY & DRUG DESIGN. - ISSN 1747-0285. - (2012), pp. 1-11. [10.1111/j.1747-0285.2012.01397x]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/458910
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