We have developed a technique and a prototype for ??-rays and ??-rays quantitative imaging of biological samples which have been radioactively labeled. The prototype is based on a solid state pixel detector, bump-bonded to a low threshold, single particle counting chip: the detector we used is 200-??m thick GaAs, with pixel size 170 ??m. In this paper we describe an experiment that shows the capability of monitoring a dynamic process. Specifically, [14C]L-Leucine uptake by eggs of mollusk cephalopod Octopus vulgaris and the consequent migration of marker into the ooplasm was followed
Quantitative dynamic imaging of biological processes with solid state radiation detectors / L., Abate; Bertolucci, Ennio; Conti, Maurizio; DI COSMO, Anna; C., Di Cristo; Mettivier, Giovanni; Montesi, MARIA CRISTINA; Russo, Paolo. - 1:(1999), pp. 208-211. (Intervento presentato al convegno NUCLEAR SCIENCE SYMPOSIUM & MEDICAL IMAGING CONFERENCE. tenutosi a Seattle, WA, USA nel 24-30/10/1999) [10.1109/NSSMIC.1999.842477].
Quantitative dynamic imaging of biological processes with solid state radiation detectors
BERTOLUCCI, ENNIO;CONTI, MAURIZIO;DI COSMO, ANNA;METTIVIER, GIOVANNI;MONTESI, MARIA CRISTINA;RUSSO, PAOLO
1999
Abstract
We have developed a technique and a prototype for ??-rays and ??-rays quantitative imaging of biological samples which have been radioactively labeled. The prototype is based on a solid state pixel detector, bump-bonded to a low threshold, single particle counting chip: the detector we used is 200-??m thick GaAs, with pixel size 170 ??m. In this paper we describe an experiment that shows the capability of monitoring a dynamic process. Specifically, [14C]L-Leucine uptake by eggs of mollusk cephalopod Octopus vulgaris and the consequent migration of marker into the ooplasm was followedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
