We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.

Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast / Mettivier, Giovanni; Russo, Paolo; Cesarelli, Mario; Ospizio, R.; Passeggio, G.; Roscilli, L.; Pontoriere, G.; Rocco, R.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 629:1(2011), pp. 350-356. [10.1016/j.nima.2010.10.093]

Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast

METTIVIER, GIOVANNI;RUSSO, PAOLO;CESARELLI, MARIO;
2011

Abstract

We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.
2011
Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast / Mettivier, Giovanni; Russo, Paolo; Cesarelli, Mario; Ospizio, R.; Passeggio, G.; Roscilli, L.; Pontoriere, G.; Rocco, R.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 629:1(2011), pp. 350-356. [10.1016/j.nima.2010.10.093]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/456694
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