Kinetic and isotopic labeling studies provide for the first time evidence that at physiol. pH the rearrangement of dopachrome (I) to 5,6-dihydroxyindole (II) involves abstraction of the proton at position 3 and formation of the intermediate quinone-methide III.
Mechanism of the rearrangement of dopachrome to 5,6-dihydroxyindole / C., Costantini; Crescenzi, Orlando; Prota, Giuseppe. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 32:31(1991), pp. 3849-3850. [10.1016/S0040-4039(00)79394-4]
Mechanism of the rearrangement of dopachrome to 5,6-dihydroxyindole
CRESCENZI, ORLANDO;PROTA, GIUSEPPE
1991
Abstract
Kinetic and isotopic labeling studies provide for the first time evidence that at physiol. pH the rearrangement of dopachrome (I) to 5,6-dihydroxyindole (II) involves abstraction of the proton at position 3 and formation of the intermediate quinone-methide III.File in questo prodotto:
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