The relationship between segmental renal tubular sodium handling (using the renal clearance of ingested lithium as a marker of proximal tubular sodium handling) and circulating plasma levels of atrial natriuretic factor (ANF) was studied in a sample of 295 untreated men drawn from a male population at work under their usual living conditions. Plasma ANF was positively and significantly related to sodium excretion at the distal nephron, indicating that this hormone interacts with a distal renal tubular site to influence the control of sodium excretion in man.
Atrial natriuretic peptides and tubular sodium handling during normal daily life in men / Cappuccio, FRANCESCO PAOLO; Strazzullo, Pasquale; Barba, Gianvincenzo; Iacone, Roberto; M. G., Buckley; A. L., Sugden; M., Miller; G. A., Sagnella; G. A., Macgregor; Mancini, Mario. - In: JOURNAL OF HYPERTENSION SUPPLEMENT. - ISSN 0952-1178. - STAMPA. - 7:(1989), pp. S228-S229.
Atrial natriuretic peptides and tubular sodium handling during normal daily life in men.
CAPPUCCIO, FRANCESCO PAOLO;STRAZZULLO, PASQUALE;BARBA, GIANVINCENZO;IACONE, ROBERTO;MANCINI, MARIO
1989
Abstract
The relationship between segmental renal tubular sodium handling (using the renal clearance of ingested lithium as a marker of proximal tubular sodium handling) and circulating plasma levels of atrial natriuretic factor (ANF) was studied in a sample of 295 untreated men drawn from a male population at work under their usual living conditions. Plasma ANF was positively and significantly related to sodium excretion at the distal nephron, indicating that this hormone interacts with a distal renal tubular site to influence the control of sodium excretion in man.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
