An amphiphilic ruthenium-based mol. (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.

Cubosomes for ruthenium complex delivery: formulation and characterization

MANGIAPIA, GAETANO;D'ERRICO, GERARDINO;PADUANO, LUIGI
2011

Abstract

An amphiphilic ruthenium-based mol. (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/427862
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