This is part of my PhD project: an original observation that cytochrome P-450 is irreversibly inactivated during the reductive metabolism of the hepatotoxicant carbon tetrachloride by a suicidal type of mechanism involving the degradation of the prosthetic haem moiety of the enzyme.
The mechanism of the suicidal reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride / Manno, Maurizio; DE MATTEIS, F.; King, L. J.. - In: BIOCHEMICAL PHARMACOLOGY. - ISSN 0006-2952. - STAMPA. - 37:(1988), pp. 1981-1990.
The mechanism of the suicidal reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride.
MANNO, MAURIZIO;
1988
Abstract
This is part of my PhD project: an original observation that cytochrome P-450 is irreversibly inactivated during the reductive metabolism of the hepatotoxicant carbon tetrachloride by a suicidal type of mechanism involving the degradation of the prosthetic haem moiety of the enzyme.File in questo prodotto:
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