The management of Peyronie's disease: evidence-based 2010 guidelines.

INTRODUCTION: The field of Peyronie's disease is evolving and there is need for a state-of-the-art information in this area. AIM: To develop an evidence-based state-of-the-art consensus report on the management of Peyronie's disease. METHODS: To provide state-of-the-art knowledge regarding the prevalence, etiology, medical and surgicalmanagement of Peyronie's Disease, representing the opinion of leading experts developed in a consensus process over a 2-year period. MAIN OUTCOME MEASURES: Expert opinion was based on grading of evidence-based medical literature, widespread internal committee discussion, public presentation, and debate. CONCLUSIONS: The real etiology of Peyronie's disease and the mechanisms of formation of the plaque still remain obscure. Although conservative management is obtaining a progressively larger consensus among the experts, surgical correction still remains the mainstay treatment for this condition.