Micro-Raman spectroscopy on human mammary epithelial cells irradiated by different doses of X-rays

A Micro-Raman spectroscopic investigation has been performed on human mammary epithelial cells irradiated with different doses of X-ray. Results show that this experimental approach can detect radiation-induced changes in structure, protein, nucleic acid, lipid, and carbohydrate content. Micro-Raman spectroscopy appears to be a very sensitive technique to detect molecular changes even in single human cells following exposure to ionising radiation.