Nine ophiuroid species from different geographical areas have been analyzed for their polar steroid content. Six new sulfated polyhydroxysteroids have been isolated, together with six known compounds of this type previously reported from brittle scars. The new steroids possess C-21 and 3 alpha- sulfate groups, which are distinctive features of the steroid sulfates of ophiuroids. Hydroxylation at C-2, C-4, and C-11 and the presence of double bonds at C-5 are further features of the new steroids. The structures of the new compounds were solved by spectroscopic analysis.
On the composition of sulfated polyhydroxysteroids in some ophiuroids and the structure determination ofsix new constituents / D'Auria, MARIA VALERIA; Gomez Paloma, L.; Minale, L.; Riccio, R.; Zampella, Angela. - In: JOURNAL OF NATURAL PRODUCTS. - ISSN 0163-3864. - STAMPA. - 58:2(1995), pp. 189-196. [10.1021/np50116a005]
On the composition of sulfated polyhydroxysteroids in some ophiuroids and the structure determination ofsix new constituents
D'AURIA, MARIA VALERIA;ZAMPELLA, ANGELA
1995
Abstract
Nine ophiuroid species from different geographical areas have been analyzed for their polar steroid content. Six new sulfated polyhydroxysteroids have been isolated, together with six known compounds of this type previously reported from brittle scars. The new steroids possess C-21 and 3 alpha- sulfate groups, which are distinctive features of the steroid sulfates of ophiuroids. Hydroxylation at C-2, C-4, and C-11 and the presence of double bonds at C-5 are further features of the new steroids. The structures of the new compounds were solved by spectroscopic analysis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
