A series of oligonucleotide sequences conjugated with a variety of aromatic groups through phosphodiester linkages were synthesized showing CD spectra diagnostic of parallel-stranded, tetramolecular G-quadruplex structures.
Discovery of novel anti-HIV active G-quadruplex-forming oligonucleotides
DI FABIO, GIOVANNI;D'ONOFRIO, JENNIFER;MONTESARCHIO, DANIELA;DE NAPOLI, LORENZO
2011
Abstract
A series of oligonucleotide sequences conjugated with a variety of aromatic groups through phosphodiester linkages were synthesized showing CD spectra diagnostic of parallel-stranded, tetramolecular G-quadruplex structures.File in questo prodotto:
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