This article will focus on patients with Graves disease, toxic adenoma and toxic multinodular goiter, and will compare the cardiovascular risks associated with these diseases. Patients with toxic multinodular goiter have a higher cardiovascular risk than do patients with Graves disease, although cardiovascular complications in both groups are differentially influenced by the patient's age and the cause of hyperthyroidism. Atrial fibrillation, atrial enlargement and congestive heart failure are important cardiac complications of hyperthyroidism and are prevalent in patients aged > or = 60 years with toxic multinodular goiter, particularly in those with underlying cardiac disease. An increased risk of stroke is common in patients > 65 years of age with atrial fibrillation. Graves disease is linked with autoimmune complications, such as cardiac valve involvement, pulmonary arterial hypertension and specific cardiomyopathy. Consequently, the etiology of hyperthyroidism must be established to enable correct treatment of the disease and the cardiovascular complications.

Cardiovascular involvement in patients with different causes of hyperthyroidism / Biondi, Bernadette; Kahaly, G. J.. - In: NATURE REVIEWS. ENDOCRINOLOGY. - ISSN 1759-5029. - ELETTRONICO. - 6(8):8(2010), pp. 431-443. [10.1038/nrendo.2010.105]

Cardiovascular involvement in patients with different causes of hyperthyroidism.

BIONDI, BERNADETTE;
2010

Abstract

This article will focus on patients with Graves disease, toxic adenoma and toxic multinodular goiter, and will compare the cardiovascular risks associated with these diseases. Patients with toxic multinodular goiter have a higher cardiovascular risk than do patients with Graves disease, although cardiovascular complications in both groups are differentially influenced by the patient's age and the cause of hyperthyroidism. Atrial fibrillation, atrial enlargement and congestive heart failure are important cardiac complications of hyperthyroidism and are prevalent in patients aged > or = 60 years with toxic multinodular goiter, particularly in those with underlying cardiac disease. An increased risk of stroke is common in patients > 65 years of age with atrial fibrillation. Graves disease is linked with autoimmune complications, such as cardiac valve involvement, pulmonary arterial hypertension and specific cardiomyopathy. Consequently, the etiology of hyperthyroidism must be established to enable correct treatment of the disease and the cardiovascular complications.
2010
Cardiovascular involvement in patients with different causes of hyperthyroidism / Biondi, Bernadette; Kahaly, G. J.. - In: NATURE REVIEWS. ENDOCRINOLOGY. - ISSN 1759-5029. - ELETTRONICO. - 6(8):8(2010), pp. 431-443. [10.1038/nrendo.2010.105]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/378010
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