OBJECTIVES: To examine whether waist circumference (WC) and body-mass index (BMI) can predict long-term mortality in elderly subjects with and without chronic heart failure (CHF). DESIGN: Longitudinal evaluation with a 12-year followup. SETTING: Campania, a region of southern Italy. PARTICIPANTS: One thousand three hundred thirty-two subjects aged 65 and older selected from the electoral rolls of Campania. MEASUREMENTS: The relationship between WC or BMI and mortality during a 12-year follow-up in 125 subjects with and 1,143 subjects without CHF. RESULTS: Mortality increased as WC increased in elderly subjects without CHF (from 47.8% to 56.7%, P5.01), and the increase was even greater in patients with CHF (from 58.1% to 82.0%, P5.01). In contrast, mortality decreased as BMI increased in elderly subjects without CHF (from 53.8% to 46.1%, P0 5.046) but not in those with CHF. According to Cox regression analysis, BMI protected against long-term mortality in the absence but not in the presence of CHF. In the absence of CHF,WC was associated with a 2% increased risk of long-term mortality for each 1-cm greaterWC(Hazard Ratio (HR)51.02, 95%confidence interval (CI)51.01–1.03; Po.001), versus 5% increased in the presence of CHF (HR51.06, 95% CI51.02–1.10; Po.001). CONCLUSION: WC, but not BMI, is predictive of longterm mortality in elderly individuals with CHF and to a lesser extent in those without CHF. J Am Geriatr Soc 58:1433–1440, 2010.
Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure / Testa, G; Cacciatore, F; Galizia, G; Della Morte, D; Mazzella, F; Langellotto, A; Russo, S; Gargiulo, G; De Santis, D; Ferrara, Nicola; Rengo, Franco; Abete, Pasquale. - In: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. - ISSN 0002-8614. - ELETTRONICO. - 58:(2010), pp. 1433-1440.
Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure.
Cacciatore F;FERRARA, NICOLA;RENGO, FRANCO;ABETE, PASQUALE
2010
Abstract
OBJECTIVES: To examine whether waist circumference (WC) and body-mass index (BMI) can predict long-term mortality in elderly subjects with and without chronic heart failure (CHF). DESIGN: Longitudinal evaluation with a 12-year followup. SETTING: Campania, a region of southern Italy. PARTICIPANTS: One thousand three hundred thirty-two subjects aged 65 and older selected from the electoral rolls of Campania. MEASUREMENTS: The relationship between WC or BMI and mortality during a 12-year follow-up in 125 subjects with and 1,143 subjects without CHF. RESULTS: Mortality increased as WC increased in elderly subjects without CHF (from 47.8% to 56.7%, P5.01), and the increase was even greater in patients with CHF (from 58.1% to 82.0%, P5.01). In contrast, mortality decreased as BMI increased in elderly subjects without CHF (from 53.8% to 46.1%, P0 5.046) but not in those with CHF. According to Cox regression analysis, BMI protected against long-term mortality in the absence but not in the presence of CHF. In the absence of CHF,WC was associated with a 2% increased risk of long-term mortality for each 1-cm greaterWC(Hazard Ratio (HR)51.02, 95%confidence interval (CI)51.01–1.03; Po.001), versus 5% increased in the presence of CHF (HR51.06, 95% CI51.02–1.10; Po.001). CONCLUSION: WC, but not BMI, is predictive of longterm mortality in elderly individuals with CHF and to a lesser extent in those without CHF. J Am Geriatr Soc 58:1433–1440, 2010.File | Dimensione | Formato | |
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