Many DNA mutation-based diseases recognised in Campania have recently been related to toxic substances in illegal dumping areas. We performed a comet assay on edible frog erythrocytes to evaluate DNA damage. Differences in genotoxic parameters were observed among populations. We show that severe DNA damage occurred in the north Campania where the emergence of environmental waste exploded recently. Although a similar magnitude of genotoxic damage was observed in some southern populations, it is attributable to a massive pesticide pollution related to intensive farming. The frog species analysed seems to be a good bioindicator for detecting genotoxic effects of chemical environmental hazards.

Frogs, sentinels of DNA damage induced by pollution in Naples and the neighbouring Provinces / Maselli, Valeria; Polese, Gianluca; Daniela, Rippa; Ligrone, Roberto; Rakesh Kumar Rastogi, ; Fulgione, Domenico. - In: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. - ISSN 0147-6513. - STAMPA. - 73:7(2010), pp. 1525-1529. [10.1016/j.ecoenv.2010.05.011]

Frogs, sentinels of DNA damage induced by pollution in Naples and the neighbouring Provinces

Valeria Maselli
Primo
;
POLESE, GIANLUCA
Secondo
;
FULGIONE, DOMENICO
Ultimo
2010

Abstract

Many DNA mutation-based diseases recognised in Campania have recently been related to toxic substances in illegal dumping areas. We performed a comet assay on edible frog erythrocytes to evaluate DNA damage. Differences in genotoxic parameters were observed among populations. We show that severe DNA damage occurred in the north Campania where the emergence of environmental waste exploded recently. Although a similar magnitude of genotoxic damage was observed in some southern populations, it is attributable to a massive pesticide pollution related to intensive farming. The frog species analysed seems to be a good bioindicator for detecting genotoxic effects of chemical environmental hazards.
2010
Frogs, sentinels of DNA damage induced by pollution in Naples and the neighbouring Provinces / Maselli, Valeria; Polese, Gianluca; Daniela, Rippa; Ligrone, Roberto; Rakesh Kumar Rastogi, ; Fulgione, Domenico. - In: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. - ISSN 0147-6513. - STAMPA. - 73:7(2010), pp. 1525-1529. [10.1016/j.ecoenv.2010.05.011]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/368237
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