In this paper we report the 1st case of a congenital intracranial mesenchymal chondrosarcoma in a 2-month-old infant, apparently present at birth. A magnetic resonance image showed a large left parietal solid mass, while microscopy revealed a mixture of undifferentiated small cells and mature hyaline cartilage islands, positive for vimentin, S-100, and CD99. A surgical excision was performed but the patient died after a few weeks as a result of a rapid relapse of the tumor. We also review the pediatric cases (in patients less than 20 years old) of extraskeletal (intracranial) mesenchymal chondrosarcomas of the literature, with a focus on the most recent cytogenetic and immunohistochemical studies.
Congenital intracranial mesenchymal chondrosarcoma: case report and review of the literature in pediatric patients / R., De Cecio; I., Migliaccio; J., Falleti; DEL BASSO DE CARO, Marialaura; Pettinato, Guido. - In: PEDIATRIC AND DEVELOPMENTAL PATHOLOGY. - ISSN 1093-5266. - STAMPA. - 11:4(2008), pp. 309-313. [10.2350/07-05-0279.1]
Congenital intracranial mesenchymal chondrosarcoma: case report and review of the literature in pediatric patients.
DEL BASSO DE CARO, MARIALAURA;PETTINATO, GUIDO
2008
Abstract
In this paper we report the 1st case of a congenital intracranial mesenchymal chondrosarcoma in a 2-month-old infant, apparently present at birth. A magnetic resonance image showed a large left parietal solid mass, while microscopy revealed a mixture of undifferentiated small cells and mature hyaline cartilage islands, positive for vimentin, S-100, and CD99. A surgical excision was performed but the patient died after a few weeks as a result of a rapid relapse of the tumor. We also review the pediatric cases (in patients less than 20 years old) of extraskeletal (intracranial) mesenchymal chondrosarcomas of the literature, with a focus on the most recent cytogenetic and immunohistochemical studies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
