BACKGROUND: Continual surveillance based on patch test results has proved useful for the identification of contact allergy. OBJECTIVES: To provide a current view on the spectrum of contact allergy to important sensitizers across Europe. PATIENTS/METHODS: Clinical and patch test data of 19 793 patients patch tested in 2005/2006 in the 31 participating departments from 10 European countries (the European Surveillance System on Contact Allergies' (ESSCA) www.essca-dc.org) were descriptively analysed, aggregated to four European regions. RESULTS: Nickel sulfate remains the most common allergen with standardized prevalences ranging from 19.7% (central Europe) to 24.4% (southern Europe). While a number of allergens shows limited variation across the four regions, such as Myroxylon pereirae (5.3-6.8%), cobalt chloride (6.2-8.8%) or thiuram mix (1.7-2.4%), the differences observed with other allergens may hint on underlying differences in exposures, for example: dichromate 2.4% in the UK (west) versus 4.5-5.9% in the remaining EU regions, methylchloroisothiazolinone/methylisothiazolinone 4.1% in the South versus 2.1-2.7% in the remaining regions. CONCLUSIONS: Notwithstanding residual methodological variation (affecting at least some 'difficult' allergens) tackled by ongoing efforts for standardization, a comparative analysis as presented provides (i) a broad overview on contact allergy frequencies and (ii) interesting starting points for further, in-depth investigation.
The European vaseline series in 10 European Countries, 2005/2006 – Results of the European Surveillance System on contact Allergies (ESSCA). Contct Dermatitis 61:31-38, 2009 / Uter, W; Rämsch, C; Aberer, W; Ayala, F; Balato, A; Beliauskiene, A; Fortina, Ab; Bircher, A; Brasch, J; Chowdhury, Mm; Coenraads, Pj; Schuttelaar, Ml; Cooper, S; Corradin, Mt; Elsner, P; English, Js; Fartasch, M; Mahler, V; Frosch, Pj; Fuchs, T; Gawkrodger, Dj; Gimènez-Arnau, Am; Green, Cm; Horne, Hl; Jolanki, R; King, Cm; Krêcisz, B; Kiec-Swierczynska, M; Ormerod, Ad; Orton, Di; Peserico, A; Rantanen, T; Rustemeyer, T; Sansom, Je; Simon, D; Statham, Bn; Wilkinson, M; Schnuch, A.. - In: CONTACT DERMATITIS. - ISSN 0105-1873. - 61:(2009), pp. 32-38. [10.1111/j.1600-0536.2009.01572.x.]
The European vaseline series in 10 European Countries, 2005/2006 – Results of the European Surveillance System on contact Allergies (ESSCA). Contct Dermatitis 61:31-38, 2009.
Ayala F;Balato A;
2009
Abstract
BACKGROUND: Continual surveillance based on patch test results has proved useful for the identification of contact allergy. OBJECTIVES: To provide a current view on the spectrum of contact allergy to important sensitizers across Europe. PATIENTS/METHODS: Clinical and patch test data of 19 793 patients patch tested in 2005/2006 in the 31 participating departments from 10 European countries (the European Surveillance System on Contact Allergies' (ESSCA) www.essca-dc.org) were descriptively analysed, aggregated to four European regions. RESULTS: Nickel sulfate remains the most common allergen with standardized prevalences ranging from 19.7% (central Europe) to 24.4% (southern Europe). While a number of allergens shows limited variation across the four regions, such as Myroxylon pereirae (5.3-6.8%), cobalt chloride (6.2-8.8%) or thiuram mix (1.7-2.4%), the differences observed with other allergens may hint on underlying differences in exposures, for example: dichromate 2.4% in the UK (west) versus 4.5-5.9% in the remaining EU regions, methylchloroisothiazolinone/methylisothiazolinone 4.1% in the South versus 2.1-2.7% in the remaining regions. CONCLUSIONS: Notwithstanding residual methodological variation (affecting at least some 'difficult' allergens) tackled by ongoing efforts for standardization, a comparative analysis as presented provides (i) a broad overview on contact allergy frequencies and (ii) interesting starting points for further, in-depth investigation.File | Dimensione | Formato | |
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