The first practical access to 4-hydroxy-6-(2-amino-2-carboxyethyl)benzothiazole and 4-hydroxy-7-(2-amino-2-carboxyethyl)benzothiazole (1b and 2b) and the corresponding 2-carboxy-derivs. 1a and 2a is reported, involving one-pot sequential Zn2+-assisted biomimetic oxidn. of -dopa and -cysteine, 5-S-cysteinyldopa or 2-S-cysteinyldopa.
Biologically inspired one-pot access routes to 4-hydroxybenzothiazole amino acids, red hair-specific markers of UV susceptibility and skin cancer risk / Greco, G.; Panzella, Lucia; Napolitano, Alessandra; D'Ischia, Marco. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 50:25(2009), pp. 3095-3097. [10.1016/j.tetlet.2009.04.041]
Biologically inspired one-pot access routes to 4-hydroxybenzothiazole amino acids, red hair-specific markers of UV susceptibility and skin cancer risk.
PANZELLA, LUCIA;NAPOLITANO, ALESSANDRA;D'ISCHIA, MARCO
2009
Abstract
The first practical access to 4-hydroxy-6-(2-amino-2-carboxyethyl)benzothiazole and 4-hydroxy-7-(2-amino-2-carboxyethyl)benzothiazole (1b and 2b) and the corresponding 2-carboxy-derivs. 1a and 2a is reported, involving one-pot sequential Zn2+-assisted biomimetic oxidn. of -dopa and -cysteine, 5-S-cysteinyldopa or 2-S-cysteinyldopa.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
