Abstract: This paper is concerned with a novel algorithm to study networks of biological clocks. A new set of conditions is established that can be used to verify whether an existing network synchronizes or to give guidelines to construct a new synthetic network of biological oscillators that synchronize. The methodology uses the so-called contraction theory from dynamical system theory and Gershgorin disk theorem. The strategy is validated on two examples: a model of glycolisis in yeast cells and a synthetic network of repressilators that synchronizes.
How to synchronize Biological Clocks / G., Russo; DI BERNARDO, Mario. - In: JOURNAL OF COMPUTATIONAL BIOLOGY. - ISSN 1066-5277. - STAMPA. - 16:2(2009), pp. 379-393. [10.1089/cmb.2008.21TT]
How to synchronize Biological Clocks
DI BERNARDO, MARIO
2009
Abstract
Abstract: This paper is concerned with a novel algorithm to study networks of biological clocks. A new set of conditions is established that can be used to verify whether an existing network synchronizes or to give guidelines to construct a new synthetic network of biological oscillators that synchronize. The methodology uses the so-called contraction theory from dynamical system theory and Gershgorin disk theorem. The strategy is validated on two examples: a model of glycolisis in yeast cells and a synthetic network of repressilators that synchronizes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
