Background and Objectives: Instability of hemoglobin levels during epoetin therapy is a new problem in hemodialysis. We evaluated extent and correlates of time in target, that is, the time spent with hemoglobin 11 g/dl during the first year of epoetin and its association with renal survival. Conclusions: In chronic kidney disease, time in target during the first year of epoetin therapy is frequently short depending not only on time to target but also on post-target hemoglobin reductions, correlates with male gender, timing, and intensity of initial therapy and is coupled with better renal survival.
Stability of target hemoglobin levels during the first year of epoetin treatment in patients with chronic kidney disease / De Nicola, L; Conte, G; Chiodini, P; Cianciaruso, Bruno; Pota, Andrea; Bellizzi, V; Tirino, G; Avino, D; Catapano, F; Minutolo, R.. - In: CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. - ISSN 1555-905X. - STAMPA. - 2(5):5(2007), pp. 938-946. [10.2215/CJN.01690407]
Stability of target hemoglobin levels during the first year of epoetin treatment in patients with chronic kidney disease.
CIANCIARUSO, BRUNO;POTA, ANDREA;
2007
Abstract
Background and Objectives: Instability of hemoglobin levels during epoetin therapy is a new problem in hemodialysis. We evaluated extent and correlates of time in target, that is, the time spent with hemoglobin 11 g/dl during the first year of epoetin and its association with renal survival. Conclusions: In chronic kidney disease, time in target during the first year of epoetin therapy is frequently short depending not only on time to target but also on post-target hemoglobin reductions, correlates with male gender, timing, and intensity of initial therapy and is coupled with better renal survival.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
