The results of a pharmacological investigation on a series of meta-substituted benzyltrimethylammonium salts possessing an antimuscarinic activity are reported. Correlative analysis shows that the pharmacodynamic activity is a function of the hydrophobic-lipophilic parameter associated with the substituent.
Correlation analysis in a set of X-benzyltrimethylammonium derivatives with antimuscarinic activity / M., De Amici; C., De Micheli; P., Pratesi; E., Grana; M. G., Santagostino; Cappello, Brunella; C., Silipo; A., Vittoria. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - STAMPA. - 42:(1987), pp. 409-424.
Correlation analysis in a set of X-benzyltrimethylammonium derivatives with antimuscarinic activity.
CAPPELLO, BRUNELLA;
1987
Abstract
The results of a pharmacological investigation on a series of meta-substituted benzyltrimethylammonium salts possessing an antimuscarinic activity are reported. Correlative analysis shows that the pharmacodynamic activity is a function of the hydrophobic-lipophilic parameter associated with the substituent.File in questo prodotto:
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