The "in vitro" aneuploidy of peripheral lymphocytes in 13 members of a family affected by familial polyposis coli and in 5 patients affected by familial adenomatosis and belonging to other two families, was examined. The increase in aneuploidy of lymphocytes was significant only in 6 of the 13 members of the family (2 affected by polyposis and 4 not affected) and in all 5 patients with polyposis. Aneuploidy could be, for these reasons, a marker for polyposis.
Aneuploidy of lymphocytes in familial polyposis coli / Bucci, Luigi; Salfi, R; Gentile, Maurizio; Raia, Valeria; Mazzeo, F.. - In: THE ITALIAN JOURNAL OF SURGICAL SCIENCES. - ISSN 0392-3525. - STAMPA. - 14:3(1984), pp. 201-205.
Aneuploidy of lymphocytes in familial polyposis coli.
BUCCI, LUIGI;GENTILE, MAURIZIO;RAIA, VALERIA;
1984
Abstract
The "in vitro" aneuploidy of peripheral lymphocytes in 13 members of a family affected by familial polyposis coli and in 5 patients affected by familial adenomatosis and belonging to other two families, was examined. The increase in aneuploidy of lymphocytes was significant only in 6 of the 13 members of the family (2 affected by polyposis and 4 not affected) and in all 5 patients with polyposis. Aneuploidy could be, for these reasons, a marker for polyposis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
