Forty-one patients with advanced breast cancer were given carboplatin and vinorelbine as second-line therapy. Overall objective response rate was 46% (95% confidence interval 26-56%). Myelotoxicity was the most frequently observed toxic effect; grade III-IV leucopenia occurred in 46% of the patients. Our regimen is active as second-line chemotherapy for advanced breast cancer and warrants further evaluation.

A phase II study of carboplatin and vinorelbine as second-line treatment for advanced breast cancer / Iaffaioli, R.V., Tortoriello, A., Facchini, G., Santangelo, M., De Sena, G., Gesue, G., Bucci, L., Scaramellino, G., Anastasio, E., Finizio, A.. - In: BRITISH JOURNAL OF CANCER. - ISSN 0007-0920. - STAMPA. - 72:5(1995), pp. 1256-1258.

A phase II study of carboplatin and vinorelbine as second-line treatment for advanced breast cancer.

SANTANGELO, MICHELE;BUCCI, LUIGI;
1995

Abstract

Forty-one patients with advanced breast cancer were given carboplatin and vinorelbine as second-line therapy. Overall objective response rate was 46% (95% confidence interval 26-56%). Myelotoxicity was the most frequently observed toxic effect; grade III-IV leucopenia occurred in 46% of the patients. Our regimen is active as second-line chemotherapy for advanced breast cancer and warrants further evaluation.
1995
A phase II study of carboplatin and vinorelbine as second-line treatment for advanced breast cancer / Iaffaioli, R.V., Tortoriello, A., Facchini, G., Santangelo, M., De Sena, G., Gesue, G., Bucci, L., Scaramellino, G., Anastasio, E., Finizio, A.. - In: BRITISH JOURNAL OF CANCER. - ISSN 0007-0920. - STAMPA. - 72:5(1995), pp. 1256-1258.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/337247
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