Stagonospora cirsii Davis, a fungal pathogen isolated from Cirsium arvense (commonly called Canada thistle) and proposed as a potential mycoherbicide of this perennial noxious weed, produces phytotoxic metabolites in liquid and solid cultures. Stagonolide, the main phytotoxic metabolite, and five new related nonenolides, named stagonolides B-F, were isolated from the fungus. When grown on solid culture, nonenolide yields increased. A further four nonenolides were isolated and characterized by spectroscopy. Three were new compounds and named stagonolides G-I, and the fourth was identified as modiolide A, previously isolated from Paraphaeosphaeria sp., a fungus separated from the horse mussel. Leaf disk-puncture assays at 1 mg/mL of stagonolides H-I and modiolide A were phytotoxic to C. arvense. Only stagonolide H inhibited chicory seedling root growth. The most potent toxin, stagonolide H, indicated selectivity when tested on leaves of eight different plants: Canada thistle was most sensitive to the compound.

Stagonolide G-I and modiolide A, nonenolides produced by Stagonospora cirsii, a potential mycoherbicide for Cirsium arvense” Journal of Natural Products, 2008, 71, 1897-1901 / Evidente, Antonio; Cimmino, Alessio; A., Berestetskiy; Andolfi, Anna; A., Motta. - In: JOURNAL OF NATURAL PRODUCTS. - ISSN 0163-3864. - 71:(2008), pp. 1897-1901.

Stagonolide G-I and modiolide A, nonenolides produced by Stagonospora cirsii, a potential mycoherbicide for Cirsium arvense” Journal of Natural Products, 2008, 71, 1897-1901.

EVIDENTE, ANTONIO;CIMMINO, ALESSIO;ANDOLFI, ANNA;
2008

Abstract

Stagonospora cirsii Davis, a fungal pathogen isolated from Cirsium arvense (commonly called Canada thistle) and proposed as a potential mycoherbicide of this perennial noxious weed, produces phytotoxic metabolites in liquid and solid cultures. Stagonolide, the main phytotoxic metabolite, and five new related nonenolides, named stagonolides B-F, were isolated from the fungus. When grown on solid culture, nonenolide yields increased. A further four nonenolides were isolated and characterized by spectroscopy. Three were new compounds and named stagonolides G-I, and the fourth was identified as modiolide A, previously isolated from Paraphaeosphaeria sp., a fungus separated from the horse mussel. Leaf disk-puncture assays at 1 mg/mL of stagonolides H-I and modiolide A were phytotoxic to C. arvense. Only stagonolide H inhibited chicory seedling root growth. The most potent toxin, stagonolide H, indicated selectivity when tested on leaves of eight different plants: Canada thistle was most sensitive to the compound.
2008
Stagonolide G-I and modiolide A, nonenolides produced by Stagonospora cirsii, a potential mycoherbicide for Cirsium arvense” Journal of Natural Products, 2008, 71, 1897-1901 / Evidente, Antonio; Cimmino, Alessio; A., Berestetskiy; Andolfi, Anna; A., Motta. - In: JOURNAL OF NATURAL PRODUCTS. - ISSN 0163-3864. - 71:(2008), pp. 1897-1901.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/334684
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