Fusapyrone (FP), an antifungal natural compd., was tested against the three main ochratoxigenic species of the Aspergillus section Nigri. The MICs at 24 h were 6.0, 11.6, and 9.9 g/mL for Aspergillus carbonarius, Aspergillus tubingensis, and Aspergillus niger, resp. Strong inhibition of growth and morphol. changes were still obsd. at half the MIC after 7 days. The application of a 100 g/mL FP soln. in a lab. assay on artificially inoculated grapes resulted in a significant redn. (up to 6 orders of magnitude) of A. carbonarius CFU counts. Dramatic redns. of the ochratoxin A (OTA) content, compared to the content of the pos. control (av. amt. of OTA, 112.5 ng/g of grape; three expts.), were obtained with the application of either 100 or 50 g/mL of FP (0.6 or 5.1 ng/g of grape, resp.).
Inhibition of species of the Aspergillus section Nigri and ochratoxin A production in grapes by fusapyrone” Applied and Environmental Microbiology, 2248-2253 (2008) / M., Favilla; M., Pascale; A., Ricelli; Evidente, Antonio; Amalfitano, Carmine; C., Altomare. - In: APPLIED AND ENVIRONMENTAL MICROBIOLOGY. - ISSN 0099-2240. - STAMPA. - (2008), pp. 2248-2253.
Inhibition of species of the Aspergillus section Nigri and ochratoxin A production in grapes by fusapyrone” Applied and Environmental Microbiology, 2248-2253 (2008).
EVIDENTE, ANTONIO;AMALFITANO, CARMINE;
2008
Abstract
Fusapyrone (FP), an antifungal natural compd., was tested against the three main ochratoxigenic species of the Aspergillus section Nigri. The MICs at 24 h were 6.0, 11.6, and 9.9 g/mL for Aspergillus carbonarius, Aspergillus tubingensis, and Aspergillus niger, resp. Strong inhibition of growth and morphol. changes were still obsd. at half the MIC after 7 days. The application of a 100 g/mL FP soln. in a lab. assay on artificially inoculated grapes resulted in a significant redn. (up to 6 orders of magnitude) of A. carbonarius CFU counts. Dramatic redns. of the ochratoxin A (OTA) content, compared to the content of the pos. control (av. amt. of OTA, 112.5 ng/g of grape; three expts.), were obtained with the application of either 100 or 50 g/mL of FP (0.6 or 5.1 ng/g of grape, resp.).File | Dimensione | Formato | |
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