Novel amphiphilic cyclic disaccharide analogues, in which the saccharide units are connected through stable phosphodiester linkages (CyPLOS, Cyclic Phosphate-Linked OligoSaccharides) and decorated with long lipophilic tentacles at the 2- and 3-OH moieties, have been synthesized. Their propensity to selfaggregation has been investigated by means of 1H and 31P NMR experiments, making it possible to determine for these macrocycles critical aggregation concentration values in the millimolar range.
Novel Amphiphilic Cyclic Oligosaccharides: Synthesis and Self-Aggregation Properties / C., Coppola; V., Saggiomo; DI FABIO, Giovanni; DE NAPOLI, Lorenzo; Montesarchio, Daniela. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - ELETTRONICO. - 72:25(2007), pp. 9679-9689. [10.1021/jo7017087]
Novel Amphiphilic Cyclic Oligosaccharides: Synthesis and Self-Aggregation Properties
DI FABIO, GIOVANNI;DE NAPOLI, LORENZO;MONTESARCHIO, DANIELA
2007
Abstract
Novel amphiphilic cyclic disaccharide analogues, in which the saccharide units are connected through stable phosphodiester linkages (CyPLOS, Cyclic Phosphate-Linked OligoSaccharides) and decorated with long lipophilic tentacles at the 2- and 3-OH moieties, have been synthesized. Their propensity to selfaggregation has been investigated by means of 1H and 31P NMR experiments, making it possible to determine for these macrocycles critical aggregation concentration values in the millimolar range.| File | Dimensione | Formato | |
|---|---|---|---|
|
joc9679-07.pdf
non disponibili
Tipologia:
Documento in Post-print
Licenza:
Accesso privato/ristretto
Dimensione
234.94 kB
Formato
Adobe PDF
|
234.94 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
