The preparative synthesis of a 3-acetamido-3,6-dideoxy-D-galactopyranose N-phenyl-trifluoroacetimidate donor has been accomplished using as key step a silica gel mediated cyclization of an epoxytrichloroacetimidate, while other more conventional routes to aminosugars failed. Test glycosylations with the N-phenyl-trifluoroacetimidate donor are also reported.
First preparative synthesis of a 3-acetamido-3,6-dideoxy-D-galactopyranose glycosyl donor via intramolecular cyclization of an epoxytrichloroacetimidate / Carabellese, Antonella; Bedini, Emiliano; Iadonisi, Alfonso; Parrilli, Michelangelo. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 45:(2004), pp. 4445-4448.
First preparative synthesis of a 3-acetamido-3,6-dideoxy-D-galactopyranose glycosyl donor via intramolecular cyclization of an epoxytrichloroacetimidate
CARABELLESE, ANTONELLA;BEDINI, EMILIANO;IADONISI, ALFONSO;PARRILLI, MICHELANGELO
2004
Abstract
The preparative synthesis of a 3-acetamido-3,6-dideoxy-D-galactopyranose N-phenyl-trifluoroacetimidate donor has been accomplished using as key step a silica gel mediated cyclization of an epoxytrichloroacetimidate, while other more conventional routes to aminosugars failed. Test glycosylations with the N-phenyl-trifluoroacetimidate donor are also reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.