A new lycorine-type alkaloid, named (-)-amarbellisine (I), was isolated from the bulbs of Egyptian Amaryllis belladonna L. together with the well known alkaloids (-)-lycorine, (-)-pancracine, (+)-vittatine, (+)-11-hydroxyvittatine, and (+)-hippeastrine. The new alkaloid, contg. the pyrrolo[de]phenanthridine ring system, was essentially characterized by spectroscopic and optical methods, and proved to be the 2-methoxy-3a,4,5,7,11b,11c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridinol. By using HPTLC technique we also carried out a comparative study of the relative and total alkaloidal content at two different stages of plant growth. Finally, the antimicrobial activity of the isolated alkaloids was assayed

Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt

EVIDENTE, ANTONIO;ANDOLFI, ANNA;
2004

Abstract

A new lycorine-type alkaloid, named (-)-amarbellisine (I), was isolated from the bulbs of Egyptian Amaryllis belladonna L. together with the well known alkaloids (-)-lycorine, (-)-pancracine, (+)-vittatine, (+)-11-hydroxyvittatine, and (+)-hippeastrine. The new alkaloid, contg. the pyrrolo[de]phenanthridine ring system, was essentially characterized by spectroscopic and optical methods, and proved to be the 2-methoxy-3a,4,5,7,11b,11c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridinol. By using HPTLC technique we also carried out a comparative study of the relative and total alkaloidal content at two different stages of plant growth. Finally, the antimicrobial activity of the isolated alkaloids was assayed
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/201095
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