Investigation of the bark of Croton eluteria Bennett for biologically active compounds has led to the isolation the new prenylbisabolane 3, whose structure was assed by spectroscopic methods. The corresponding known enone 4 and the eudesmane sesquiterpene 2 were also obtained. Compound 3 proved active in selectively inhibiting the induction of NF-KB by tumor necrosis factor- in T cells.

A prenylbisabolane with NF-kB inhibiting properties from cascarilla (Croton eluteria) / Campagnuolo, Claudio; Fattorusso, Ernesto; F., Petrucci; TAGLIALATELA SCAFATI, Orazio; G., Appendino; N., Marquez; E., Munoz. - In: BIOORGANIC & MEDICINAL CHEMISTRY. - ISSN 0968-0896. - STAMPA. - 13:(2005), pp. 4238-4242. [10.1016/j.bmc.2005.04.025]

A prenylbisabolane with NF-kB inhibiting properties from cascarilla (Croton eluteria).

CAMPAGNUOLO, CLAUDIO;FATTORUSSO, ERNESTO;TAGLIALATELA SCAFATI, ORAZIO;
2005

Abstract

Investigation of the bark of Croton eluteria Bennett for biologically active compounds has led to the isolation the new prenylbisabolane 3, whose structure was assed by spectroscopic methods. The corresponding known enone 4 and the eudesmane sesquiterpene 2 were also obtained. Compound 3 proved active in selectively inhibiting the induction of NF-KB by tumor necrosis factor- in T cells.
2005
A prenylbisabolane with NF-kB inhibiting properties from cascarilla (Croton eluteria) / Campagnuolo, Claudio; Fattorusso, Ernesto; F., Petrucci; TAGLIALATELA SCAFATI, Orazio; G., Appendino; N., Marquez; E., Munoz. - In: BIOORGANIC & MEDICINAL CHEMISTRY. - ISSN 0968-0896. - STAMPA. - 13:(2005), pp. 4238-4242. [10.1016/j.bmc.2005.04.025]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/200724
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