Dermatite allergica da contatto delle palpebre da topici oftalmici. Il ruolo dei B-bloccanti: problemi di diagnosi e gestione

We report a study performed with 64 patients with an adverse drug reaction (ADR) history who were admitted to hospital for drug tolerance testing, and who were also patch tested with drugs currently suggested and used by the "ESCD working party on drug skin testing in cutaneous adverse drug reactions (ESCD-WPD)". Three positive patch test reactions were observed in two patients, namely a boy presenting with a maculo-papular rash and who was found to be amoxycillin and ampicillin positive and a girl with diffuse urticaria found to be erythromycin positive. The few positive patch test reactions reported confirm that such a procedure is highly sensitive, particularly in maculo-papular rashes, eczematous reactions and fixed drug eruptions, but that it has a low sensitivity in urticarioid or anaphylactic reactions.