Several genes encoding salivary components of the mosquito Anopheles gambiae were identified using a selective trapping approach. Among these, five corresponded to genes expressed specifically in female glands and their role may possibly be linked to blood-feeding. Our collection included a fourth member of the D7 protein family and two polypeptides that showed weak similarity to anti-coagulants from distantly related species. Moreover, we identified two additional members of a novel group of proteins that we named glandins. The isolation of tissue-specific genes represents a first step toward a deeper molecular analysis of mosquito salivary secretions.
Novel cDNAs encoding salivary proteins from the malaria vector Anopheles gambiae / Lanfrancotti, A; Lombardo, F; Santolamazza, F; Veneri, M; Castrignano', T; Coluzzi, M; Arca', Bruno. - In: FEBS LETTERS. - ISSN 0014-5793. - STAMPA. - 517:1-3(2002), pp. 67-71. [10.1016/S0014-5793(02)02578-4]
Novel cDNAs encoding salivary proteins from the malaria vector Anopheles gambiae.
ARCA', BRUNO
2002
Abstract
Several genes encoding salivary components of the mosquito Anopheles gambiae were identified using a selective trapping approach. Among these, five corresponded to genes expressed specifically in female glands and their role may possibly be linked to blood-feeding. Our collection included a fourth member of the D7 protein family and two polypeptides that showed weak similarity to anti-coagulants from distantly related species. Moreover, we identified two additional members of a novel group of proteins that we named glandins. The isolation of tissue-specific genes represents a first step toward a deeper molecular analysis of mosquito salivary secretions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.