Cerebrospinal fluid (CSF) and serum concentrations of beta-2-microglobulin (beta-2-m) were evaluated in 19 patients with clinically definite multiple sclerosis (MS), in 21 with AIDS dementia complex (ADC), and in 20 subjects with other neurological diseases (OND). CSF beta-2-m and CSF/serum beta-2-m ratio were significantly higher in the patients with ADC than in the MS and OND patients. The CSF and serum levels of beta-2-m in MS patients were not significantly different from those of OND patients. These findings indicate that CSF beta-2-m and CSF/serum ratio may be a useful marker in the diagnosis of ADC. In MS patients the beta-2-m CSF determinations are of no value.

Cerebrospinal fluid beta-2-microglobulin in multiple sclerosis and AIDS dementia complex / Carrieri, Pb; Indaco, A; Maiorino, A; Buscaino, Ga; Ponticiello, Antonio; Liberti, A; Perrella, O.. - In: NEUROLOGICAL RESEARCH. - ISSN 0161-6412. - STAMPA. - 14:(1992), pp. 282-283.

Cerebrospinal fluid beta-2-microglobulin in multiple sclerosis and AIDS dementia complex.

PONTICIELLO, ANTONIO;
1992

Abstract

Cerebrospinal fluid (CSF) and serum concentrations of beta-2-microglobulin (beta-2-m) were evaluated in 19 patients with clinically definite multiple sclerosis (MS), in 21 with AIDS dementia complex (ADC), and in 20 subjects with other neurological diseases (OND). CSF beta-2-m and CSF/serum beta-2-m ratio were significantly higher in the patients with ADC than in the MS and OND patients. The CSF and serum levels of beta-2-m in MS patients were not significantly different from those of OND patients. These findings indicate that CSF beta-2-m and CSF/serum ratio may be a useful marker in the diagnosis of ADC. In MS patients the beta-2-m CSF determinations are of no value.
1992
Cerebrospinal fluid beta-2-microglobulin in multiple sclerosis and AIDS dementia complex / Carrieri, Pb; Indaco, A; Maiorino, A; Buscaino, Ga; Ponticiello, Antonio; Liberti, A; Perrella, O.. - In: NEUROLOGICAL RESEARCH. - ISSN 0161-6412. - STAMPA. - 14:(1992), pp. 282-283.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/157008
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