Isoguanosine 1 was obtained in 76% overall yield starting from 2',3',5'-tri-O-acetylxanthosine 3 in a reaction involving the chloro derivative 4 and the N-(purin-6-yl) pyridinium salt derivative 8 which also proved to be new and valuable synthetic intermediates in the obtainment of C-6-substituted xanthosine derivatives.
Improved synthesis of isoguanosine and 6-substituted xanthosine derivatives / DE NAPOLI, Lorenzo; Montesarchio, Daniela; Piccialli, Gennaro; C., Santacroce; Varra, Michela. - In: JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. I. - ISSN 0300-922X. - ELETTRONICO. - 1(1995), pp. 15-17. [10.1039/p19950000015]
Improved synthesis of isoguanosine and 6-substituted xanthosine derivatives
DE NAPOLI, LORENZO;MONTESARCHIO, DANIELA;PICCIALLI, GENNARO;VARRA, MICHELA
1995
Abstract
Isoguanosine 1 was obtained in 76% overall yield starting from 2',3',5'-tri-O-acetylxanthosine 3 in a reaction involving the chloro derivative 4 and the N-(purin-6-yl) pyridinium salt derivative 8 which also proved to be new and valuable synthetic intermediates in the obtainment of C-6-substituted xanthosine derivatives.File in questo prodotto:
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