The urokinase-mediated plasminogen activation (PA) system has been shown to play a key role in cell migration and tissue invasion by regulating both cell-associated proteolysis and cell-cell and cell-matrix interactions. The expression and activity of the components of this complex system are strictly regulated. The control of the expression occurs both at transcriptional and post-transcriptional levels. This review is focused on the post-transcriptional regulation of gene expression of all components of the PA system.
Post-transcriptional regulation of gene expression in the plasminogen activation system / Montuori, Nunzia; G. ROSSI AND P., Ragno. - In: BIOLOGICAL CHEMISTRY. - ISSN 1431-6730. - STAMPA. - 383:(2002), pp. 47-53.
Post-transcriptional regulation of gene expression in the plasminogen activation system.
MONTUORI, NUNZIA;
2002
Abstract
The urokinase-mediated plasminogen activation (PA) system has been shown to play a key role in cell migration and tissue invasion by regulating both cell-associated proteolysis and cell-cell and cell-matrix interactions. The expression and activity of the components of this complex system are strictly regulated. The control of the expression occurs both at transcriptional and post-transcriptional levels. This review is focused on the post-transcriptional regulation of gene expression of all components of the PA system.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
