Phototherapy of allergic contact dermatitis by narrow-band ultraviolet B

Phototherapy with narrow-band ultraviolet B (NB-UVB) (peak at 311 nm) has been recently used for the treatment of some eczematous diseases, such as atopic dermatitis. It has been demonstrated that NB-UVB is as efficacious as broad-band UVB, but with less side effects. The efficacy of NB-UVB phototherapy in inhibiting both patch test response and contact dermatitis of the hands in 8 nickel sensitive patients was evaluated. Clinical scores showed a significant improvement (57%). Moreover, irradiated areas were less reactive than untreated skin to patch test with nickel sulphate 5%. No side effects were observed. These data suggest than NB-UVB should be considered as a possible therapy for allergic contact dermatitis.