A digital autoradiography system based on double sided silicon strip detectors (1.6 × 1.6 mm2 active surface with 100 μm pitch) has been developed and successfully tested with beta-emitting tracers. It is shown here that the system is able to perform imaging of organic material with specific sensitivity as small as 0.002 nCi/mm2, and to record activity measurements with good linearity in the range 0.002–20 nCi/mm2. Autoradiographic images of clusters of mammary cells marked with ortho-(32P)phosphate, obtained with an exposure time of about 10 min are presented.
Autoradiography with silicon strip detectors / E., Bertolucci; M., Conti; Grossi, Gianfranco; G., Madonna; E., Mancini; Russo, Paolo; M., Caria; P., Randaccio; A., DEL GUERRA; M., Gambaccini; R., Marchesini; M., Marziani; A., Taibi; R., Beccherle; M. G., Bisogni; U., Bottigli; M. E., Fantacci; V., Rosso; A., Stefanini; R., Tripiccione; S. R., Amendolia. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 381:2-3(1996), pp. 527-530. [10.1016/S0168-9002(96)00736-X]
Autoradiography with silicon strip detectors
GROSSI, GIANFRANCO;RUSSO, PAOLO;
1996
Abstract
A digital autoradiography system based on double sided silicon strip detectors (1.6 × 1.6 mm2 active surface with 100 μm pitch) has been developed and successfully tested with beta-emitting tracers. It is shown here that the system is able to perform imaging of organic material with specific sensitivity as small as 0.002 nCi/mm2, and to record activity measurements with good linearity in the range 0.002–20 nCi/mm2. Autoradiographic images of clusters of mammary cells marked with ortho-(32P)phosphate, obtained with an exposure time of about 10 min are presented.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
