A digital autoradiography system based on double sided silicon strip detectors (1.6 × 1.6 mm2 active surface with 100 μm pitch) has been developed and successfully tested with beta-emitting tracers. It is shown here that the system is able to perform imaging of organic material with specific sensitivity as small as 0.002 nCi/mm2, and to record activity measurements with good linearity in the range 0.002–20 nCi/mm2. Autoradiographic images of clusters of mammary cells marked with ortho-(32P)phosphate, obtained with an exposure time of about 10 min are presented.

Autoradiography with silicon strip detectors / E., B., M., C., Grossi, G., G., M., E., M., Russo, P., M., C., P., R., A., D.G., M., G., R., M., M., M., A., T., R., B., M. G., B., U., B., M. E., F., V., R., A., S., R., T., et al.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 381:2-3(1996), pp. 527-530. [10.1016/S0168-9002(96)00736-X]

Autoradiography with silicon strip detectors

GROSSI, GIANFRANCO;RUSSO, PAOLO;
1996

Abstract

A digital autoradiography system based on double sided silicon strip detectors (1.6 × 1.6 mm2 active surface with 100 μm pitch) has been developed and successfully tested with beta-emitting tracers. It is shown here that the system is able to perform imaging of organic material with specific sensitivity as small as 0.002 nCi/mm2, and to record activity measurements with good linearity in the range 0.002–20 nCi/mm2. Autoradiographic images of clusters of mammary cells marked with ortho-(32P)phosphate, obtained with an exposure time of about 10 min are presented.
1996
Autoradiography with silicon strip detectors / E., B., M., C., Grossi, G., G., M., E., M., Russo, P., M., C., P., R., A., D.G., M., G., R., M., M., M., A., T., R., B., M. G., B., U., B., M. E., F., V., R., A., S., R., T., et al.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 381:2-3(1996), pp. 527-530. [10.1016/S0168-9002(96)00736-X]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/146722
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