A cell line derived from a pleiomorphic liposarcoma (LSA) secretes a factor exhibiting specific and selective oncotoxic properties. This factor, a variant isoform of manganese superoxide dismutase (MnSOD), by injection in mammary cancer affected cats and dogs, was internalized only in the tumor cells. So, when labelled, it could be used as tumor marker or as radiopharmaceuticals.

A new viable form of recombinant Manganese Superoxide Dismutase (rMnSOD ) as a new anticancer molecule.

PICA, ALESSANDRA;OCCHIELLO, ANTONELLA;LORIZIO, ROBERTO;
2006

Abstract

A cell line derived from a pleiomorphic liposarcoma (LSA) secretes a factor exhibiting specific and selective oncotoxic properties. This factor, a variant isoform of manganese superoxide dismutase (MnSOD), by injection in mammary cancer affected cats and dogs, was internalized only in the tumor cells. So, when labelled, it could be used as tumor marker or as radiopharmaceuticals.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/120265
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