Objectives: Incisional hernia is a complication after abdominal surgery and is particularly challenging in patients with ascites because of increased intra-abdominal pressure, impaired wound healing, and infection risk. Evidence on surgical repair remains limited, particularly for incisional rather than umbilical hernias. Methods: This retrospective multicenter study included 31 cirrhotic patients with ascites(22 males, 9 females; 45-72 years) who underwent incisional hernia repair between 2000 and 2025 at three tertiary General and Emergency Surgery Units. Liver disease severity was assessed using the Child-Pugh classification. Following preoperative ascites optimization, repair was performed with primary suture or mesh reinforcement. Primary outcomes were perioperative morbidity and mortality; secondary outcome was hernia recurrence. Results: Perioperative mortality occurred in 5 patients (16.1 %), all with advanced liver disease. Major complications occurred in 8 patients (25.8 %), while minor complications developed in 10 (32.3 %), mainly surgicalsite infection, seroma or hematoma, and postoperative ileus. After a median followup of 26 months, hernia recurrence occurred in 11 patients (35.5 %) andwas higher after primary suture than mesh repair. Conclusions: Elective repair isfeasible in selected patients after ascites optimization. Mesh reinforcement provides greater durability when infection risk is acceptable. Patient selection and perioperative management remain essential.

Incisional hernia repair in cirrhotic patients with ascites: a multicenter retrospective experience / Fernicola, A., Angelini, P., Ricciardelli, L., Santangelo, A., Santangelo, D., Satea Shafeea, M., Crocetto, F., Calogero, A., Schiavone, V., Benassai, G., Quarto, G., Costa, G., Caricato, M., Santangelo, M.. - In: JOURNAL OF BASIC AND CLINICAL PHYSIOLOGY AND PHARMACOLOGY. - ISSN 0792-6855. - Online ahead of print:(2026). [10.1515/jbcpp-2026-0173]

Incisional hernia repair in cirrhotic patients with ascites: a multicenter retrospective experience

Fernicola, Agostino;Ricciardelli, Luigi;Santangelo, Domenico;Crocetto, Felice;Calogero, Armando;Schiavone, Vincenzo;Benassai, Giacomo;Quarto, Gennaro;Caricato, Marco;
2026

Abstract

Objectives: Incisional hernia is a complication after abdominal surgery and is particularly challenging in patients with ascites because of increased intra-abdominal pressure, impaired wound healing, and infection risk. Evidence on surgical repair remains limited, particularly for incisional rather than umbilical hernias. Methods: This retrospective multicenter study included 31 cirrhotic patients with ascites(22 males, 9 females; 45-72 years) who underwent incisional hernia repair between 2000 and 2025 at three tertiary General and Emergency Surgery Units. Liver disease severity was assessed using the Child-Pugh classification. Following preoperative ascites optimization, repair was performed with primary suture or mesh reinforcement. Primary outcomes were perioperative morbidity and mortality; secondary outcome was hernia recurrence. Results: Perioperative mortality occurred in 5 patients (16.1 %), all with advanced liver disease. Major complications occurred in 8 patients (25.8 %), while minor complications developed in 10 (32.3 %), mainly surgicalsite infection, seroma or hematoma, and postoperative ileus. After a median followup of 26 months, hernia recurrence occurred in 11 patients (35.5 %) andwas higher after primary suture than mesh repair. Conclusions: Elective repair isfeasible in selected patients after ascites optimization. Mesh reinforcement provides greater durability when infection risk is acceptable. Patient selection and perioperative management remain essential.
2026
Incisional hernia repair in cirrhotic patients with ascites: a multicenter retrospective experience / Fernicola, A., Angelini, P., Ricciardelli, L., Santangelo, A., Santangelo, D., Satea Shafeea, M., Crocetto, F., Calogero, A., Schiavone, V., Benassai, G., Quarto, G., Costa, G., Caricato, M., Santangelo, M.. - In: JOURNAL OF BASIC AND CLINICAL PHYSIOLOGY AND PHARMACOLOGY. - ISSN 0792-6855. - Online ahead of print:(2026). [10.1515/jbcpp-2026-0173]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/1063495
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