A biomimetic model for protein/lipid radical damage is described. The model shows that the protein degradation is accompanied by trans lipid isomerization due to thiyl radicals, derived from sulfur-containing residues and diffused through the lipid bilayer. γ-Irradiation was used to obtain free radical generation and lysozyme was chosen as enzyme example.
RADIATION DAMAGE OF LYSOZYME IN A BIOMIMETIC MODEL: SOME INSIGHTS BY RAMAN SPECTROSCOPY / A., Torreggiani; M., Tamba; I., Manco; FARAONE MENNELLA, MARIA ROSARIA; C., Ferreri; C., Chatgilialoglu. - In: JOURNAL OF MOLECULAR STRUCTURE. - ISSN 0022-2860. - ELETTRONICO. - 744-747:(2005), pp. 767-773. [10.1016/jmolstruct2004.11.076]
RADIATION DAMAGE OF LYSOZYME IN A BIOMIMETIC MODEL: SOME INSIGHTS BY RAMAN SPECTROSCOPY.
FARAONE MENNELLA, MARIA ROSARIA;
2005
Abstract
A biomimetic model for protein/lipid radical damage is described. The model shows that the protein degradation is accompanied by trans lipid isomerization due to thiyl radicals, derived from sulfur-containing residues and diffused through the lipid bilayer. γ-Irradiation was used to obtain free radical generation and lysozyme was chosen as enzyme example.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
