A biomimetic model for protein/lipid radical damage is described. The model shows that the protein degradation is accompanied by trans lipid isomerization due to thiyl radicals, derived from sulfur-containing residues and diffused through the lipid bilayer. γ-Irradiation was used to obtain free radical generation and lysozyme was chosen as enzyme example.

RADIATION DAMAGE OF LYSOZYME IN A BIOMIMETIC MODEL: SOME INSIGHTS BY RAMAN SPECTROSCOPY.

FARAONE MENNELLA, MARIA ROSARIA;
2005

Abstract

A biomimetic model for protein/lipid radical damage is described. The model shows that the protein degradation is accompanied by trans lipid isomerization due to thiyl radicals, derived from sulfur-containing residues and diffused through the lipid bilayer. γ-Irradiation was used to obtain free radical generation and lysozyme was chosen as enzyme example.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/104501
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