Summary Paper on the 2026 European Association of Urology Guidelines on the Management of Non-neurogenic Male Lower Urinary Tract Symptoms

Context: The European Association of Urology (EAU) male lower urinary tract symptoms (MLUTS) Guideline Panel has updated its evidence-based guidelines and recommendations 2026 for the management of MLUTS. Objectives: To present a summary of the 2026 MLUTS guideline updated with standardised methodology to provide reproducible evidence for the management of MLUTS. Evidence acquisition: For the 2026 EAU Guidelines on non-neurogenic male LUTS, evidence was identified through a structured review across Medline, EMBASE, and the Cochrane Library, prioritising systematic reviews with meta-analysis, randomised controlled trials and prospective comparative studies. Literature search was conducted from 1 May 2023 to 1 May 2025. A detailed search strategy is available at https://uroweb.org/guidelines/management-of-non-neurogenic-male-luts/publications-appendices. Evidence synthesis: Clinical practice recommendations were updated across all chapters of the male LUTS guideline based on a structured literature search. Included studies consisted predominantly of systematic reviews, randomised controlled trials, and prospective comparative studies. Updates addressed diagnostic evaluation, conservative and surgical management of benign prostatic obstruction, and for the first time, a dedicated section on voiding dysfunction in young men. Conclusions: The 2026 MLUTS Guidelines have been updated by the multidisciplinary Panel of experts employing methodological standards to provide a contemporary evidence base for the management of MLUTS. Patient summary: The European Association of Urology Male Lower Urinary Tract Symptoms Guidelines Panel has reviewed the available scientific evidence on non-neurogenic male lower urinary tract symptoms to develop international recommendations for the diagnosis and management of men with LUTS.