Continued investigation of the polar extracts of the marine sponge Latrunculia sp. has resulted in the discovery of callipeltins J-M. The new structures were determined by interpretation of their NMR and MS data. The stereochemistry of the unusual 3-methylglutamine residue in callipeltins J and K was secured by stereoselective synthesis and Marfey's LC-MS analysis.

Isolation and structural elucidation of callipeltins J-M: antifungal peptides from the marine sponge Latrunculia sp

SEPE, VALENTINA;D'AURIA, MARIA VALERIA;ZAMPELLA, ANGELA
2007

Abstract

Continued investigation of the polar extracts of the marine sponge Latrunculia sp. has resulted in the discovery of callipeltins J-M. The new structures were determined by interpretation of their NMR and MS data. The stereochemistry of the unusual 3-methylglutamine residue in callipeltins J and K was secured by stereoselective synthesis and Marfey's LC-MS analysis.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/103696
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