Lactophorin is a major whey protein in camelid milk that prevents fat globule aggregation and inhibits spontaneous lipolysis. It has also been proposed to play immunological functions, including the prevention of mastitis in lactating animals and the suppression of pathogen replication in the respiratory and gastrointestinal tracts of suckling offspring. In this study, we explore the genetic variation of the glycosylation-dependent cell adhesion molecule-1 (GlyCam-1) gene in camelids, which encodes lactophorin, and examine the functional implications of the identified polymorphisms
Across deserts and Andes: a genetic exploration of GlyCam-1 in domestic camelids / Letaief, N.; Alhaddad, H.; Lühken, G.; Gaspa, G.; Versace, C.; Miretti, S.; Cosenza, G.; Zhang, Y.; Pauciullo, A.. - In: BMC VETERINARY RESEARCH. - ISSN 1746-6148. - 22:article number 55(2026), pp. 1-19. [10.1186/s12917-025-05196-8]
Across deserts and Andes: a genetic exploration of GlyCam-1 in domestic camelids
COSENZA G.Membro del Collaboration Group
;
2026
Abstract
Lactophorin is a major whey protein in camelid milk that prevents fat globule aggregation and inhibits spontaneous lipolysis. It has also been proposed to play immunological functions, including the prevention of mastitis in lactating animals and the suppression of pathogen replication in the respiratory and gastrointestinal tracts of suckling offspring. In this study, we explore the genetic variation of the glycosylation-dependent cell adhesion molecule-1 (GlyCam-1) gene in camelids, which encodes lactophorin, and examine the functional implications of the identified polymorphismsI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
