MASCOLO, LUIGI
MASCOLO, LUIGI
DIPARTIMENTO DI NEUROSCIENZE E SCIENZE RIPRODUTTIVE ED ODONTOSTOMATOLOGICHE
p38/Sp1/Sp4/HDAC4/BDNF Axis Is a Novel Molecular Pathway of the Neurotoxic Effect of the Methylmercury
2017 Guida, Natascia; Laudati, Giusy; Mascolo, Luigi; Valsecchi, Valeria; Sirabella, Rossana; Selleri, Carmine; DI RENZO, GIANFRANCO MARIA LUIGI; Canzoniero, Lorella M. T; Formisano, Luigi
MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter
2015 Formisano, Luigi; Guida, Natascia; Laudati, Guisy; Mascolo, Luigi; DI RENZO, GIANFRANCO MARIA LUIGI; Canzoniero, Lorella M. T.
The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death
2017 Guida, N; Laudati, G; Serani, Angelo; Mascolo, L; Molinaro, P; Montuori, P; Di Renzo, G; Canzoniero, Lmt; Formisano, L.
The miR206-JunD circuit mediates the neurotoxic effect of methylmercury in cortical neurons
2018 Guida, Natascia; Valsecchi, Valeria; Laudati, Giusy; Serani, Angelo; Mascolo, Luigi; Molinaro, Pasquale; Montuori, Paolo; Di Renzo, Gianfranco; Canzoniero, Lorella M T; Formisano, Luigi
Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway
2019 Laudati, Giusy; Mascolo, Luigi; Guida, Natascia; Sirabella, Rossana; Pizzorusso, Vincenzo; Bruzzaniti, Sara; Serani, Angelo; Di Renzo, Gianfranco; Canzoniero, Lorella M. T.; Formisano, Luigi
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage
2020 Formisano, L.; Laudati, G.; Guida, N.; Mascolo, L.; Serani, A.; Cuomo, O.; Cantile, M.; Boscia, F.; Molinaro, P.; Anzilotti, S.; Pizzorusso, V.; Di Renzo, G.; Pignataro, G.; Annunziato, L.
MC1568 Inhibits Thimerosal-Induced Apoptotic Cell Death by Preventing HDAC4 Up-Regulation in Neuronal Cells and in Rat Prefrontal Cortex
2016 Guida, Natascia; Laudati, Giusy; Mascolo, Luigi; Cuomo, Ornella; Anzilotti, Serenella; Sirabella, Rossana; Santopaolo, Marianna; Galgani, Mario; Montuori, Paolo; Di Renzo, Gianfranco; Canzoniero, Lorella M T; Formisano, Luigi
CD4+ T Cell Defects in a Mulibrey Patient With Specific TRIM37 Mutations
2020 Bruzzaniti, Sara; Cirillo, Emilia; Prencipe, Rosaria; Giardino, Giuliana; Lepore, Maria Teresa; Garziano, Federica; Perna, Francesco; Procaccini, Claudio; Mascolo, Luigi; Pagano, Cristina; Fattorusso, Valentina; Mozzillo, Enza; Bifulco, Maurizio; Matarese, Giuseppe; Franzese, Adriana; Pignata, Claudio; Galgani, Mario
GATA3 (GATA-binding protein 3)/KMT2A (lysine-methyltransferase-2A) complex by increasing H3K4-3me (trimethylated lysine-4 of histone-3) upregulates NCX3 (Na+-Ca2+exchanger 3) transcription and contributes to ischemic preconditioning neuroprotection
2021 Guida, N.; Mascolo, L.; Serani, A.; Cuomo, O.; Anzilotti, S.; Brancaccio, P.; Pignataro, G.; Molinaro, P.; Annunziato, L.; Formisano, L.
The Transcriptional Complex Sp1/KMT2A by Up-Regulating Restrictive Element 1 Silencing Transcription Factor Accelerates Methylmercury-Induced Cell Death in Motor Neuron-Like NSC34 Cells Overexpressing SOD1-G93A
2021 Guida, N.; Sanguigno, L.; Mascolo, L.; Calabrese, L.; Serani, A.; Molinaro, P.; Lau, C. G.; Annunziato, L.; Formisano, L.
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death
2023 Sanguigno, Luca; Guida, Natascia; Anzilotti, Serenella; Cuomo, Ornella; Mascolo, Luigi; Serani, Angelo; Brancaccio, Paola; Pennacchio, Giuseppina; Licastro, Ester; Pignataro, Giuseppe; Molinaro, Pasquale; Annunziato, Lucio; Formisano, Luigi
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| p38/Sp1/Sp4/HDAC4/BDNF Axis Is a Novel Molecular Pathway of the Neurotoxic Effect of the Methylmercury | 1.1 Articolo in rivista | 2017 | Guida, Natascia; Laudati, Giusy; Mascolo, Luigi; Valsecchi, Valeria; Sirabella, Rossana; Selleri, Carmine; DI RENZO, GIANFRANCO MARIA LUIGI; Canzoniero, Lorella M. T; Formisano, Luigi | |
| MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter | 1.1 Articolo in rivista | 2015 | Formisano, Luigi; Guida, Natascia; Laudati, Guisy; Mascolo, Luigi; DI RENZO, GIANFRANCO MARIA LUIGI; Canzoniero, Lorella M. T. | |
| The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death | 1.1 Articolo in rivista | 2017 | Guida, N; Laudati, G; Serani, Angelo; Mascolo, L; Molinaro, P; Montuori, P; Di Renzo, G; Canzoniero, Lmt; Formisano, L. | |
| The miR206-JunD circuit mediates the neurotoxic effect of methylmercury in cortical neurons | 1.1 Articolo in rivista | 2018 | Guida, Natascia; Valsecchi, Valeria; Laudati, Giusy; Serani, Angelo; Mascolo, Luigi; Molinaro, Pasquale; Montuori, Paolo; Di Renzo, Gianfranco; Canzoniero, Lorella M T; Formisano, Luigi | |
| Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway | 1.1 Articolo in rivista | 2019 | Laudati, Giusy; Mascolo, Luigi; Guida, Natascia; Sirabella, Rossana; Pizzorusso, Vincenzo; Bruzzaniti, Sara; Serani, Angelo; Di Renzo, Gianfranco; Canzoniero, Lorella M. T.; Formisano, Luigi | |
| HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage | 1.1 Articolo in rivista | 2020 | Formisano, L.; Laudati, G.; Guida, N.; Mascolo, L.; Serani, A.; Cuomo, O.; Cantile, M.; Boscia, F.; Molinaro, P.; Anzilotti, S.; Pizzorusso, V.; Di Renzo, G.; Pignataro, G.; Annunziato, L. | |
| MC1568 Inhibits Thimerosal-Induced Apoptotic Cell Death by Preventing HDAC4 Up-Regulation in Neuronal Cells and in Rat Prefrontal Cortex | 1.1 Articolo in rivista | 2016 | Guida, Natascia; Laudati, Giusy; Mascolo, Luigi; Cuomo, Ornella; Anzilotti, Serenella; Sirabella, Rossana; Santopaolo, Marianna; Galgani, Mario; Montuori, Paolo; Di Renzo, Gianfranco; Canzoniero, Lorella M T; Formisano, Luigi | |
| CD4+ T Cell Defects in a Mulibrey Patient With Specific TRIM37 Mutations | 1.1 Articolo in rivista | 2020 | Bruzzaniti, Sara; Cirillo, Emilia; Prencipe, Rosaria; Giardino, Giuliana; Lepore, Maria Teresa; Garziano, Federica; Perna, Francesco; Procaccini, Claudio; Mascolo, Luigi; Pagano, Cristina; Fattorusso, Valentina; Mozzillo, Enza; Bifulco, Maurizio; Matarese, Giuseppe; Franzese, Adriana; Pignata, Claudio; Galgani, Mario | |
| GATA3 (GATA-binding protein 3)/KMT2A (lysine-methyltransferase-2A) complex by increasing H3K4-3me (trimethylated lysine-4 of histone-3) upregulates NCX3 (Na+-Ca2+exchanger 3) transcription and contributes to ischemic preconditioning neuroprotection | 1.1 Articolo in rivista | 2021 | Guida, N.; Mascolo, L.; Serani, A.; Cuomo, O.; Anzilotti, S.; Brancaccio, P.; Pignataro, G.; Molinaro, P.; Annunziato, L.; Formisano, L. | |
| The Transcriptional Complex Sp1/KMT2A by Up-Regulating Restrictive Element 1 Silencing Transcription Factor Accelerates Methylmercury-Induced Cell Death in Motor Neuron-Like NSC34 Cells Overexpressing SOD1-G93A | 1.1 Articolo in rivista | 2021 | Guida, N.; Sanguigno, L.; Mascolo, L.; Calabrese, L.; Serani, A.; Molinaro, P.; Lau, C. G.; Annunziato, L.; Formisano, L. | |
| Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death | 1.1 Articolo in rivista | 2023 | Sanguigno, Luca; Guida, Natascia; Anzilotti, Serenella; Cuomo, Ornella; Mascolo, Luigi; Serani, Angelo; Brancaccio, Paola; Pennacchio, Giuseppina; Licastro, Ester; Pignataro, Giuseppe; Molinaro, Pasquale; Annunziato, Lucio; Formisano, Luigi |