FRALDI, ALESSANDRO
FRALDI, ALESSANDRO
DIPARTIMENTO DI SCIENZE MEDICHE TRASLAZIONALI
Functional inactivation of Cdk9 through oligomerization chain reaction
2003 Napolitano, Giuliana; Mazzocco, A.; Fraldi, Alessandro; Majello, Barbara; Lania, Luigi
MAQ1 and 7K RNA interact with CDK9/Cyclin T complexes in a transcription-dependent manner
2003 Michels, Aa; Nguyen, Vn; Fraldi, Alessandro; Labas, V; Edwards, M; Bonnet, F; Lania, Luigi; Bensaude, O.
Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer.
2005 Dulac, C; Michels, Aa; Fraldi, Alessandro; Bonnet, F; Nguyen, Vt; Napolitano, Giuliana; Lania, Luigi; Bensaude, O.
Cell trafficking of SUMF1 described by functional proteomics experiments
2008 Cozzolino, M.; Monti, Maria; Fraldi, Alessandro; Zito, E.; Cosma, MARIA PIA; Pucci, Pietro
Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex.
2001 Fraldi, Alessandro; Licciardo, P; Majello, Barbara; Giordano, A; Lania, Luigi
Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases
2012 de Pablo Latorre, R; Saide, A; Polishhuck, Ev; Nusco, E; Fraldi, Alessandro; Ballabio, Andrea
Inhibition of Tat activity by the HEXIM1 protein.
2005 Fraldi, Alessandro; F., Varrone; Napolitano, Giuliana; Michels, Aa; Majello, Barbara; Bensaude, O; Lania, Luigi
Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS).
2013 Bachetti, T; Chiesa, S; Castagnola, P; Bani, D; Di Zanni, E; Omenetti, A; D'Osualdo, A; Fraldi, Alessandro; Ballabio, Andrea; Ravazzolo, R; Martini, A; Gattorno, M; Ceccherini, I.
Functional inactivation of Cdk9 through oligomerization chain reaction.
2003 Napolitano, Giuliana; Mazzocco, A; Fraldi, Alessandro; Majello, Barbara; Lania, Luigi
Transdermal spinal catheter placement in piglets: Description and validation of the technique.
2015 Lambertini, C; Ventrella, D; Barone, F; Sorrentino, Nc; Dondi, F; Fraldi, Alessandro; Giunti, M; Surace, Enrico Maria; Bacci, Ml; Romagnoli, N.
Transcription-dependent association of multiple P-TEFb units to a hexim multimer.
2005 Dulac, C; Michels, Aa; Fraldi, Alessandro; Bonnet, F; Nguyen, Vt; Napolitano, Giuliana; Lania, Luigi; Bensaude, O.
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.
2011 Medina, Dl; Fraldi, Alessandro; Bouche, V; Annunziata, F; Mansueto, G; Spampanato, C; Puri, C; Pignata, A; Martina, Ja; Sardiello, M; Palmieri, M; Polishchuk, R; Puertollano, R; Ballabio, Andrea; MEDINA SANABRIA, Diego Luis
Intracerebral Administration of Adeno-Associated Viral Vector Serotype rh.10 Carrying Human SGSH and SUMF1 cDNAs in Children with Mucopolysaccharidosis Type IIIA Disease: Results of a Phase I/II Trial.
2014 Tardieu, M; Z?rah, M; Husson, B; de Bournonville, S; Deiva, K; Adamsbaum, C; Vincent, F; Hocquemiller, M; Broissand, C; Furlan, V; Ballabio, Andrea; Fraldi, Alessandro; Crystal, Rg; Baugnon, T; Roujeau, T; Heard, Jm; Danos, O.
A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.
2013 Sorrentino, Nc; D'Orsi, L; Sambri, I; Nusco, E; Monaco, C; Spampanato, C; Polishchuk, E; Saccone, P; De Leonibus, E; Ballabio, Andrea; Fraldi, Alessandro
A comprehensive map of CNS transduction by eight recombinant adeno-associated virus serotypes upon cerebrospinal fluid administration in pigs
2016 Sorrentino, Nicolina Cristina; Maffia, Veronica; Strollo, Sandra; Cacace, Vincenzo; Romagnoli, Noemi; Manfredi, Anna; Ventrella, Domenico; Dondi, Francesco; Barone, Francesca; Giunti, Massimo; Graham, Anne Renee; Huang, Yan; Kalled, Susan L; Auricchio, Alberto; Bacci, Maria Laura; Surace, Enrico Maria; Fraldi, Alessandro
Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells
2014 Quintavalle, Cristina; Di Costanzo, S.; Zanca, Ciro; Tasset, I.; Fraldi, Alessandro; Incoronato, M.; Mirabelli, P.; Monti, Maria; Ballabio, Andrea; Pucci, Pietro; Cuervo, A. M.; Condorelli, Gerolama
Access to cerebrospinal fluid in piglets via the cisterna magna: Optimization and description of the technique
2014 Romagnoli, Noemi; Ventrella, Domenico; Giunti, Massimo; Dondi, Francesco; Sorrentino, Nicolina C.; Fraldi, Alessandro; Surace, Enrico Maria; Bacci, Maria L.
Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases
2017 Sambri, Irene; D'Alessio, Rosa; Ezhova, Yulia; Giuliano, Teresa; Sorrentino, Nicolina Cristina; Cacace, Vincenzo; De Risi, Maria; Cataldi, Mauro; Annunziato, Lucio; De Leonibus, Elvira; Fraldi, Alessandro
Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.
2008 Fraldi, Alessandro; Zito, E.; Annunziata, F.; Lombardi, A.; Cozzolino, M.; Monti, Maria; Spampanato, C.; Ballabio, Andrea; Pucci, Pietro; Sitia, R.; Cosma, M. P.
Brain Targeting in MPS-IIIA
2016 Sorrentino, Nicolina Cristina; Fraldi, Alessandro
Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
---|---|---|---|---|
Functional inactivation of Cdk9 through oligomerization chain reaction | 1.1 Articolo in rivista | 2003 | Napolitano, Giuliana; Mazzocco, A.; Fraldi, Alessandro; Majello, Barbara; Lania, Luigi | |
MAQ1 and 7K RNA interact with CDK9/Cyclin T complexes in a transcription-dependent manner | 1.1 Articolo in rivista | 2003 | Michels, Aa; Nguyen, Vn; Fraldi, Alessandro; Labas, V; Edwards, M; Bonnet, F; Lania, Luigi; Bensaude, O. | |
Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer. | 1.1 Articolo in rivista | 2005 | Dulac, C; Michels, Aa; Fraldi, Alessandro; Bonnet, F; Nguyen, Vt; Napolitano, Giuliana; Lania, Luigi; Bensaude, O. | |
Cell trafficking of SUMF1 described by functional proteomics experiments | 4.1 Articoli in Atti di convegno | 2008 | Cozzolino, M.; Monti, Maria; Fraldi, Alessandro; Zito, E.; Cosma, MARIA PIA; Pucci, Pietro | |
Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex. | 1.1 Articolo in rivista | 2001 | Fraldi, Alessandro; Licciardo, P; Majello, Barbara; Giordano, A; Lania, Luigi | |
Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases | 1.1 Articolo in rivista | 2012 | de Pablo Latorre, R; Saide, A; Polishhuck, Ev; Nusco, E; Fraldi, Alessandro; Ballabio, Andrea | |
Inhibition of Tat activity by the HEXIM1 protein. | 1.1 Articolo in rivista | 2005 | Fraldi, Alessandro; F., Varrone; Napolitano, Giuliana; Michels, Aa; Majello, Barbara; Bensaude, O; Lania, Luigi | |
Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS). | 1.1 Articolo in rivista | 2013 | Bachetti, T; Chiesa, S; Castagnola, P; Bani, D; Di Zanni, E; Omenetti, A; D'Osualdo, A; Fraldi, Alessandro; Ballabio, Andrea; Ravazzolo, R; Martini, A; Gattorno, M; Ceccherini, I. | |
Functional inactivation of Cdk9 through oligomerization chain reaction. | 1.1 Articolo in rivista | 2003 | Napolitano, Giuliana; Mazzocco, A; Fraldi, Alessandro; Majello, Barbara; Lania, Luigi | |
Transdermal spinal catheter placement in piglets: Description and validation of the technique. | 1.1 Articolo in rivista | 2015 | Lambertini, C; Ventrella, D; Barone, F; Sorrentino, Nc; Dondi, F; Fraldi, Alessandro; Giunti, M; Surace, Enrico Maria; Bacci, Ml; Romagnoli, N. | |
Transcription-dependent association of multiple P-TEFb units to a hexim multimer. | 1.1 Articolo in rivista | 2005 | Dulac, C; Michels, Aa; Fraldi, Alessandro; Bonnet, F; Nguyen, Vt; Napolitano, Giuliana; Lania, Luigi; Bensaude, O. | |
Transcriptional activation of lysosomal exocytosis promotes cellular clearance. | 1.1 Articolo in rivista | 2011 | Medina, Dl; Fraldi, Alessandro; Bouche, V; Annunziata, F; Mansueto, G; Spampanato, C; Puri, C; Pignata, A; Martina, Ja; Sardiello, M; Palmieri, M; Polishchuk, R; Puertollano, R; Ballabio, Andrea; MEDINA SANABRIA, Diego Luis | |
Intracerebral Administration of Adeno-Associated Viral Vector Serotype rh.10 Carrying Human SGSH and SUMF1 cDNAs in Children with Mucopolysaccharidosis Type IIIA Disease: Results of a Phase I/II Trial. | 1.1 Articolo in rivista | 2014 | Tardieu, M; Z?rah, M; Husson, B; de Bournonville, S; Deiva, K; Adamsbaum, C; Vincent, F; Hocquemiller, M; Broissand, C; Furlan, V; Ballabio, Andrea; Fraldi, Alessandro; Crystal, Rg; Baugnon, T; Roujeau, T; Heard, Jm; Danos, O. | |
A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA. | 1.1 Articolo in rivista | 2013 | Sorrentino, Nc; D'Orsi, L; Sambri, I; Nusco, E; Monaco, C; Spampanato, C; Polishchuk, E; Saccone, P; De Leonibus, E; Ballabio, Andrea; Fraldi, Alessandro | |
A comprehensive map of CNS transduction by eight recombinant adeno-associated virus serotypes upon cerebrospinal fluid administration in pigs | 1.1 Articolo in rivista | 2016 | Sorrentino, Nicolina Cristina; Maffia, Veronica; Strollo, Sandra; Cacace, Vincenzo; Romagnoli, Noemi; Manfredi, Anna; Ventrella, Domenico; Dondi, Francesco; Barone, Francesca; Giunti, Massimo; Graham, Anne Renee; Huang, Yan; Kalled, Susan L; Auricchio, Alberto; Bacci, Maria Laura; Surace, Enrico Maria; Fraldi, Alessandro | |
Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells | 1.1 Articolo in rivista | 2014 | Quintavalle, Cristina; Di Costanzo, S.; Zanca, Ciro; Tasset, I.; Fraldi, Alessandro; Incoronato, M.; Mirabelli, P.; Monti, Maria; Ballabio, Andrea; Pucci, Pietro; Cuervo, A. M.; Condorelli, Gerolama | |
Access to cerebrospinal fluid in piglets via the cisterna magna: Optimization and description of the technique | 1.1 Articolo in rivista | 2014 | Romagnoli, Noemi; Ventrella, Domenico; Giunti, Massimo; Dondi, Francesco; Sorrentino, Nicolina C.; Fraldi, Alessandro; Surace, Enrico Maria; Bacci, Maria L. | |
Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases | 1.1 Articolo in rivista | 2017 | Sambri, Irene; D'Alessio, Rosa; Ezhova, Yulia; Giuliano, Teresa; Sorrentino, Nicolina Cristina; Cacace, Vincenzo; De Risi, Maria; Cataldi, Mauro; Annunziato, Lucio; De Leonibus, Elvira; Fraldi, Alessandro | |
Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44. | 1.1 Articolo in rivista | 2008 | Fraldi, Alessandro; Zito, E.; Annunziata, F.; Lombardi, A.; Cozzolino, M.; Monti, Maria; Spampanato, C.; Ballabio, Andrea; Pucci, Pietro; Sitia, R.; Cosma, M. P. | |
Brain Targeting in MPS-IIIA | 1.1 Articolo in rivista | 2016 | Sorrentino, Nicolina Cristina; Fraldi, Alessandro |