Sfoglia per Autore
ER+ breast cancers resistant to prolonged neoadjuvant letrozole exhibit an E2F4 transcriptional program sensitive to CDK4/6 inhibitors
2018 Guerrero-Zotano, Angel; Stricker, Thomas; Formisano, Luigi; E Hutchinson, Katherine; Stover, Daniel G.; Lee, Kyung-min; J Schwarz, Luis; Giltnane, Jennifer M.; V Estrada, Monica; M Jansen, Valerie; Servetto, Alberto; Gavilá, Joaquín; Alejandro Pérez-Fidalgo, José; Lluch, Ana; Llombart-Cussac, Antonio; Amine Bayar, Mohamed; Michiels, Stefan; Andre, Fabrice; Arnedos, Monica; Guillem, Vicente; RUIZ-SIMON, Amparo
A Phase Ib Study of Alpelisib (BYL719), a PI3Ka-Specific Inhibitor, with Letrozole in ERþ/HER2 Metastatic Breast Cancer
2017 Mayer, Ingrid A.; Abramson, Vandana G.; Formisano, Luigi; Balko, Justin M.; Estrada, Mónica V.; Sanders, Melinda E.; Juric, Dejan; Solit, David; Berger, Michael F.; Won, Helen H.; Li, Yisheng; Cantley, Lewis C.; Winer, Eric; Arteaga, Carlos L.
An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression.
2017 Schwarz, Lj; Hutchinson, Ke; Rexer, Bn; Estrada, Mv; Gonzalez Ericsson, Pi; Sanders, Me; Dugger, Tc; Formisano, L; Guerrero-Zotano, A; Red-Brewer, M; Young, Cd; Lantto, J; Pedersen, Mw; Kragh, M; Horak, Id; Arteaga, Cl.
Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance
2017 Giltnane, Jennifer M.; Hutchinson, Katherine E.; Stricker, Thomas P.; Formisano, Luigi; Young, Christian D.; Estrada, Monica V.; Nixon, Mellissa J.; Du, Liping; Sanchez, Violeta; Ericsson, Paula Gonzalez; Kuba, Maria G.; Sanders, Melinda E.; Mu, Xinmeng J.; Van Allen, Eliezer M.; Wagle, Nikhil; Mayer, Ingrid A.; Abramson, Vandana; Gómez, Henry; Rizzo, Monica; Toy, Weiyi; Chandarlapaty, Sarat; Mayer, Erica L.; Christiansen, Jason; Murphy, Danielle; Fitzgerald, Kerry; Wang, Kai; Ross, Jeffrey S.; Miller, Vincent A.; Stephens, Phillip J.; Yelensky, Roman; Garraway, Levi; Shyr, Yu; Meszoely, Ingrid; Balko, Justin M.; Arteaga, Carlos L.
Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer
2017 Jansen, Valerie M.; Bhola, Neil E.; Bauer, Joshua A.; Formisano, Luigi; Lee, Kyung-Min; Hutchinson, Katherine E.; Witkiewicz, Agnieszka K.; Moore, Preston D.; Estrada, Mónica Valéria; Sánchez, Violeta; Ericsson, Paula G.; Sanders, Melinda E.; Pohlmann, Paula R.; Pishvaian, Michael J.; Riddle, David A.; Dugger, Teresa C.; Wei, Wenyi; Knudsen, Erik S.; Arteaga, Carlos L.
Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors
2017 Mauro, Concetta Di; Pesapane, Ada; Formisano, Luigi; Rosa, Roberta; D'Amato, Valentina; Ciciola, Paola; Servetto, Alberto; Marciano, Roberta; Orsini, Roberta Clara; Monteleone, Francesca; Zambrano, Nicola; Fontanini, Gabriella; Servadio, Adele; Pignataro, Giuseppe; Grumetto, Lucia; Lavecchia, Antonio; Bruzzese, Dario; Iaccarino, Antonino; Troncone, Giancarlo; Veneziani, BIANCA MARIA; Montuori, Nunzia; Placido, Sabino De; Bianco, Roberto
Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers
2017 Di Mauro, Concetta; Rosa, Roberta; D'Amato, Valentina; Ciciola, Paola; Servetto, Alberto; Marciano, Roberta; Orsini, Roberta Clara; Formisano, Luigi; De Falco, Sandro; Cicatiello, Valeria; Di Bonito, Maurizio; Cantile, Monica; Collina, Francesca; Chambery, Angela; Veneziani, BIANCA MARIA; De Placido, Sabino; Bianco, Roberto
Association of FGFR1 with ERαmaintains ligand-independent ER transcription and mediates resistance to estrogen deprivation in ER+ breast cancer
2017 Formisano, Luigi; Stauffer, Kimberly Mae; Young, Christian D; Bhola, Neil E; Guerrero Zotano, Angel L; Jansen, Valerie M; Estrada, Monica M; Hutchinson, Katherine E; Giltnane, Jennifer M; Schwarz, Luis J; Lu, Yao; Balko, Justin M; Deas, Olivier; Cairo, Stefano; Judde, Jean Gabriel; Mayer, Ingrid A; Sanders, Melinda; Dugger, Teresa C; Bianco, Roberto; Stricker, Thomas; Arteaga, Carlos L.
Treatment of triple-negative breast cancer with TORC1/2 inhibitors sustains a drug-resistant and notch-dependent cancer stem cell population
2016 Bhola, Neil E.; Jansen, Valerie M.; Koch, James P.; Li, Hua; Formisano, Luigi; Williams, Janice A.; Grandis, Jennifer R.; Arteaga, Carlos L.
Everolimus induces Met inactivation by disrupting the FKBP12/Met complex
2016 Raimondo, Lucia; D'Amato, Valentina; Servetto, Alberto; Rosa, Roberta; Marciano, Roberta; Formisano, Luigi; DI MAURO, Concetta; Orsini, Roberta Clara; Cascetta, Priscilla; Ciciola, Paola; DE MAIO, ANA PAULA; di Renzo, Maria Flavia; Cosconati, Sandro; Bruno, Agostino; Randazzo, Antonio; Napolitano, Filomena; Montuori, Nunzia; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto
Activating PIK3CA mutations induce an epidermal growth factor receptor (EGFR)/extracellular signal-regulated Kinase (ERK) paracrine signaling axis in basal-like breast cancer
2015 Young, Christian D.; Zimmerman, Lisa J.; Hoshino, Daisuke; Formisano, Luigi; Hanker, Ariella B.; Gatza, Michael L.; Morrison, Meghan M.; Moore, Preston D.; Whitwell, Corbin A.; Dave, Bhuvanesh; Stricker, Thomas; Bhola, Neil E.; Silva, Grace O.; Patel, Premal; Brantley-Sieders, Dana M.; Levin, Maren; Horiates, Marina; Palma, Norma A.; Wang, Kai; Stephens, Philip J.; Perou, Charles M.; Weaver, Alissa M.; O'Shaughnessy, Joyce A.; Chang, Jenny C.; Park, Ben Ho; Liebler, Daniel C.; Cook, Rebecca S.; Arteaga, Carlos L.
Mechanisms of lapatinib resistance in HER2-driven breast cancer
2015 D'Amato, Valentina; Raimondo, Lucia; Formisano, Luigi; Giuliano, Mario; DE PLACIDO, Sabino; Rosa, Roberta; Bianco, Roberto
Maintenance Treatment with Cetuximab and BAY86-9766 Increases Antitumor Efficacy of Irinotecan plus Cetuximab in Human Colorectal Cancer Xenograft Models
2015 Troiani, Teresa; Napolitano, Stefania; Martini, Giulia; Martinelli, Erika; Cardone, Claudia; Normanno, Nicola; Vitagliano, Donata; Morgillo, Floriana; Fenizia, Francesca; Lambiase, Matilde; Formisano, Luigi; Bianco, Roberto; Ciardiello, Davide; Ciardiello, Fortunato
Src inhibitors act through different mechanisms in Non-Small Cell Lung Cancer models depending on EGFR and RAS mutational status
2015 Formisano, Luigi; Valentina D'Amato, Null; Servetto, Alberto; Brillante, Simona; Raimondo, Lucia; Mauro, Concetta Di; Marciano, Roberta; Orsini, Roberta Clara; Cosconati, Sandro; Randazzo, Antonio; Parsons, Sarah; Montuori, Nunzia; Veneziani, BIANCA MARIA; Placido, Sabino De; Rosa, Roberta; Bianco, Roberto
Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models
2015 Cicatiello, Valeria; Apicella, Ivana; Tudisco, Laura; Tarallo, Valeria; Formisano, Luigi; Sandomenico, Annamaria; Kim, Younghee; Bastos Carvalho, Ana; Orlandi, Augusto; Ambati, Jayakrishna; Ruvo, Menotti; Bianco, Roberto; De Falco, Sandro
Epidermal growth factor receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models.
2014 Formisano, L; Nappi, L; Rosa, R; Marciano, R; D., Amato C; D., Amato V; Damiano, V; Raimondo, L; Iommelli, F; Scorziello, Antonella; Troncone, Giancarlo; Veneziani, BIANCA MARIA; Parsons, Sj; DE PLACIDO, Sabino; Bianco, Roberto
The dual PI3K/mTOR inhibitor PKI-587 enhances sensitivity to cetuximab in EGFR-resistant human head and neck cancer models.
2014 D'Amato, V; Rosa, R; D'Amato, C; Formisano, L; Marciano, R; Nappi, L; Raimondo, L; Di Mauro, C; Servetto, A; Fusciello, C; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto
Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cells
2014 D'Amato, C.; Rosa, R.; Marciano, R.; D'Amato, V.; Formisano, L.; Nappi, L.; Raimondo, L.; Di Mauro, C.; Servetto, A.; Fulciniti, F.; Cipolletta, A.; Bianco, C.; Ciardiello, F.; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto
P0081 Src inhibitors act through different mechanisms to cooperate with EGFR or MEK inhibitors in NSCLC models sensitive or resistant to erlotinib
2014 Raimondo, L.; Formisano, L.; Rosa, R.; D?amato, C.; D?amato, V.; Nappi, L.; Marciano, R.; Di Mauro, C.; Servetto, A.; Damiano, V.; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto
1599P - Effects of Hedgehog signaling inhibition on epithelial-stromal interactions in triple negative breast cancer cells
2014 Servetto, A.; Raimondo, L.; Formisano, L.; Marciano, R.; Di Mauro, C.; Rosa, R.; D'Amato, V.; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| ER+ breast cancers resistant to prolonged neoadjuvant letrozole exhibit an E2F4 transcriptional program sensitive to CDK4/6 inhibitors | 1.1 Articolo in rivista | 2018 | Guerrero-Zotano, Angel; Stricker, Thomas; Formisano, Luigi; E Hutchinson, Katherine; Stover, Daniel G.; Lee, Kyung-min; J Schwarz, Luis; Giltnane, Jennifer M.; V Estrada, Monica; M Jansen, Valerie; Servetto, Alberto; Gavilá, Joaquín; Alejandro Pérez-Fidalgo, José; Lluch, Ana; Llombart-Cussac, Antonio; Amine Bayar, Mohamed; Michiels, Stefan; Andre, Fabrice; Arnedos, Monica; Guillem, Vicente; RUIZ-SIMON, Amparo | |
| A Phase Ib Study of Alpelisib (BYL719), a PI3Ka-Specific Inhibitor, with Letrozole in ERþ/HER2 Metastatic Breast Cancer | 1.1 Articolo in rivista | 2017 | Mayer, Ingrid A.; Abramson, Vandana G.; Formisano, Luigi; Balko, Justin M.; Estrada, Mónica V.; Sanders, Melinda E.; Juric, Dejan; Solit, David; Berger, Michael F.; Won, Helen H.; Li, Yisheng; Cantley, Lewis C.; Winer, Eric; Arteaga, Carlos L. | |
| An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression. | 1.1 Articolo in rivista | 2017 | Schwarz, Lj; Hutchinson, Ke; Rexer, Bn; Estrada, Mv; Gonzalez Ericsson, Pi; Sanders, Me; Dugger, Tc; Formisano, L; Guerrero-Zotano, A; Red-Brewer, M; Young, Cd; Lantto, J; Pedersen, Mw; Kragh, M; Horak, Id; Arteaga, Cl. | |
| Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance | 1.1 Articolo in rivista | 2017 | Giltnane, Jennifer M.; Hutchinson, Katherine E.; Stricker, Thomas P.; Formisano, Luigi; Young, Christian D.; Estrada, Monica V.; Nixon, Mellissa J.; Du, Liping; Sanchez, Violeta; Ericsson, Paula Gonzalez; Kuba, Maria G.; Sanders, Melinda E.; Mu, Xinmeng J.; Van Allen, Eliezer M.; Wagle, Nikhil; Mayer, Ingrid A.; Abramson, Vandana; Gómez, Henry; Rizzo, Monica; Toy, Weiyi; Chandarlapaty, Sarat; Mayer, Erica L.; Christiansen, Jason; Murphy, Danielle; Fitzgerald, Kerry; Wang, Kai; Ross, Jeffrey S.; Miller, Vincent A.; Stephens, Phillip J.; Yelensky, Roman; Garraway, Levi; Shyr, Yu; Meszoely, Ingrid; Balko, Justin M.; Arteaga, Carlos L. | |
| Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer | 1.1 Articolo in rivista | 2017 | Jansen, Valerie M.; Bhola, Neil E.; Bauer, Joshua A.; Formisano, Luigi; Lee, Kyung-Min; Hutchinson, Katherine E.; Witkiewicz, Agnieszka K.; Moore, Preston D.; Estrada, Mónica Valéria; Sánchez, Violeta; Ericsson, Paula G.; Sanders, Melinda E.; Pohlmann, Paula R.; Pishvaian, Michael J.; Riddle, David A.; Dugger, Teresa C.; Wei, Wenyi; Knudsen, Erik S.; Arteaga, Carlos L. | |
| Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors | 1.1 Articolo in rivista | 2017 | Mauro, Concetta Di; Pesapane, Ada; Formisano, Luigi; Rosa, Roberta; D'Amato, Valentina; Ciciola, Paola; Servetto, Alberto; Marciano, Roberta; Orsini, Roberta Clara; Monteleone, Francesca; Zambrano, Nicola; Fontanini, Gabriella; Servadio, Adele; Pignataro, Giuseppe; Grumetto, Lucia; Lavecchia, Antonio; Bruzzese, Dario; Iaccarino, Antonino; Troncone, Giancarlo; Veneziani, BIANCA MARIA; Montuori, Nunzia; Placido, Sabino De; Bianco, Roberto | |
| Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers | 1.1 Articolo in rivista | 2017 | Di Mauro, Concetta; Rosa, Roberta; D'Amato, Valentina; Ciciola, Paola; Servetto, Alberto; Marciano, Roberta; Orsini, Roberta Clara; Formisano, Luigi; De Falco, Sandro; Cicatiello, Valeria; Di Bonito, Maurizio; Cantile, Monica; Collina, Francesca; Chambery, Angela; Veneziani, BIANCA MARIA; De Placido, Sabino; Bianco, Roberto | |
| Association of FGFR1 with ERαmaintains ligand-independent ER transcription and mediates resistance to estrogen deprivation in ER+ breast cancer | 1.1 Articolo in rivista | 2017 | Formisano, Luigi; Stauffer, Kimberly Mae; Young, Christian D; Bhola, Neil E; Guerrero Zotano, Angel L; Jansen, Valerie M; Estrada, Monica M; Hutchinson, Katherine E; Giltnane, Jennifer M; Schwarz, Luis J; Lu, Yao; Balko, Justin M; Deas, Olivier; Cairo, Stefano; Judde, Jean Gabriel; Mayer, Ingrid A; Sanders, Melinda; Dugger, Teresa C; Bianco, Roberto; Stricker, Thomas; Arteaga, Carlos L. | |
| Treatment of triple-negative breast cancer with TORC1/2 inhibitors sustains a drug-resistant and notch-dependent cancer stem cell population | 1.1 Articolo in rivista | 2016 | Bhola, Neil E.; Jansen, Valerie M.; Koch, James P.; Li, Hua; Formisano, Luigi; Williams, Janice A.; Grandis, Jennifer R.; Arteaga, Carlos L. | |
| Everolimus induces Met inactivation by disrupting the FKBP12/Met complex | 1.1 Articolo in rivista | 2016 | Raimondo, Lucia; D'Amato, Valentina; Servetto, Alberto; Rosa, Roberta; Marciano, Roberta; Formisano, Luigi; DI MAURO, Concetta; Orsini, Roberta Clara; Cascetta, Priscilla; Ciciola, Paola; DE MAIO, ANA PAULA; di Renzo, Maria Flavia; Cosconati, Sandro; Bruno, Agostino; Randazzo, Antonio; Napolitano, Filomena; Montuori, Nunzia; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto | |
| Activating PIK3CA mutations induce an epidermal growth factor receptor (EGFR)/extracellular signal-regulated Kinase (ERK) paracrine signaling axis in basal-like breast cancer | 1.1 Articolo in rivista | 2015 | Young, Christian D.; Zimmerman, Lisa J.; Hoshino, Daisuke; Formisano, Luigi; Hanker, Ariella B.; Gatza, Michael L.; Morrison, Meghan M.; Moore, Preston D.; Whitwell, Corbin A.; Dave, Bhuvanesh; Stricker, Thomas; Bhola, Neil E.; Silva, Grace O.; Patel, Premal; Brantley-Sieders, Dana M.; Levin, Maren; Horiates, Marina; Palma, Norma A.; Wang, Kai; Stephens, Philip J.; Perou, Charles M.; Weaver, Alissa M.; O'Shaughnessy, Joyce A.; Chang, Jenny C.; Park, Ben Ho; Liebler, Daniel C.; Cook, Rebecca S.; Arteaga, Carlos L. | |
| Mechanisms of lapatinib resistance in HER2-driven breast cancer | 1.2 Recensione in rivista | 2015 | D'Amato, Valentina; Raimondo, Lucia; Formisano, Luigi; Giuliano, Mario; DE PLACIDO, Sabino; Rosa, Roberta; Bianco, Roberto | |
| Maintenance Treatment with Cetuximab and BAY86-9766 Increases Antitumor Efficacy of Irinotecan plus Cetuximab in Human Colorectal Cancer Xenograft Models | 1.1 Articolo in rivista | 2015 | Troiani, Teresa; Napolitano, Stefania; Martini, Giulia; Martinelli, Erika; Cardone, Claudia; Normanno, Nicola; Vitagliano, Donata; Morgillo, Floriana; Fenizia, Francesca; Lambiase, Matilde; Formisano, Luigi; Bianco, Roberto; Ciardiello, Davide; Ciardiello, Fortunato | |
| Src inhibitors act through different mechanisms in Non-Small Cell Lung Cancer models depending on EGFR and RAS mutational status | 1.1 Articolo in rivista | 2015 | Formisano, Luigi; Valentina D'Amato, Null; Servetto, Alberto; Brillante, Simona; Raimondo, Lucia; Mauro, Concetta Di; Marciano, Roberta; Orsini, Roberta Clara; Cosconati, Sandro; Randazzo, Antonio; Parsons, Sarah; Montuori, Nunzia; Veneziani, BIANCA MARIA; Placido, Sabino De; Rosa, Roberta; Bianco, Roberto | |
| Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models | 1.1 Articolo in rivista | 2015 | Cicatiello, Valeria; Apicella, Ivana; Tudisco, Laura; Tarallo, Valeria; Formisano, Luigi; Sandomenico, Annamaria; Kim, Younghee; Bastos Carvalho, Ana; Orlandi, Augusto; Ambati, Jayakrishna; Ruvo, Menotti; Bianco, Roberto; De Falco, Sandro | |
| Epidermal growth factor receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models. | 1.1 Articolo in rivista | 2014 | Formisano, L; Nappi, L; Rosa, R; Marciano, R; D., Amato C; D., Amato V; Damiano, V; Raimondo, L; Iommelli, F; Scorziello, Antonella; Troncone, Giancarlo; Veneziani, BIANCA MARIA; Parsons, Sj; DE PLACIDO, Sabino; Bianco, Roberto | |
| The dual PI3K/mTOR inhibitor PKI-587 enhances sensitivity to cetuximab in EGFR-resistant human head and neck cancer models. | 1.1 Articolo in rivista | 2014 | D'Amato, V; Rosa, R; D'Amato, C; Formisano, L; Marciano, R; Nappi, L; Raimondo, L; Di Mauro, C; Servetto, A; Fusciello, C; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto | |
| Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cells | 1.1 Articolo in rivista | 2014 | D'Amato, C.; Rosa, R.; Marciano, R.; D'Amato, V.; Formisano, L.; Nappi, L.; Raimondo, L.; Di Mauro, C.; Servetto, A.; Fulciniti, F.; Cipolletta, A.; Bianco, C.; Ciardiello, F.; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto | |
| P0081 Src inhibitors act through different mechanisms to cooperate with EGFR or MEK inhibitors in NSCLC models sensitive or resistant to erlotinib | 1.5 Abstract in rivista | 2014 | Raimondo, L.; Formisano, L.; Rosa, R.; D?amato, C.; D?amato, V.; Nappi, L.; Marciano, R.; Di Mauro, C.; Servetto, A.; Damiano, V.; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto | |
| 1599P - Effects of Hedgehog signaling inhibition on epithelial-stromal interactions in triple negative breast cancer cells | 1.5 Abstract in rivista | 2014 | Servetto, A.; Raimondo, L.; Formisano, L.; Marciano, R.; Di Mauro, C.; Rosa, R.; D'Amato, V.; Veneziani, BIANCA MARIA; DE PLACIDO, Sabino; Bianco, Roberto |
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