Sfoglia per Autore
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
2023 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo
Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds
2023 Alfano, Antonella Ilenia; Pelliccia, Sveva; Rossino, Giacomo; Chianese, Orazio; Summa, Vincenzo; Collina, Simona; Brindisi, Margherita
Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds
2023 Alfano, A. I.; Pelliccia, S.; Rossino, G.; Chianese, O.; Summa, V.; Collina, S.; Brindisi, M.
Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation
2023 Pelliccia, Sveva; Alfano, Antonella Ilenia; Gomes Da Assunção, Beatriz Ramos; Turco, Luigia; Lembo, Francesca; Summa, Vincenzo; Buommino, Elisabetta; Brindisi, Margherita
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route
2022 Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo
Amide Bonds Meet Flow Chemistry: A Journey into Methodologies and Sustainable Evolution
2022 Alfano, A. L.; Lange, H.; Brindisi, M.
Mechanochemical Fischer indolisation: an eco-friendly design for a timeless reaction
2022 Porcheddu, A.; Mocci, R.; Brindisi, M.; Cuccu, F.; Fattuoni, C.; Delogu, F.; Colacino, E.; D'Auria, M. V.
Efficacy of selective histone deacetylase 6 inhibition in mouse models of Pseudomonas aeruginosa infection: A new glimpse for reducing inflammation and infection in cystic fibrosis
2022 Brindisi, Margherita; Barone, Simona; Rossi, Alice; Cassese, Emilia; Del Gaudio, Nunzio; Feliz Morel, Álvaro Javier; Filocamo, Gessica; Alberico, Alessia; De Fino, Ida; Gugliandolo, Davide; Babaei, Mehrad; Bove, Guglielmo; Croce, Martina; Montesano, Camilla; Altucci, Lucia; Bragonzi, Alessandra; Summa, Vincenzo
Editorial: Multi-target directed ligands for the treatment of cancer
2022 Brindisi, Margherita; Kessler, Sonja M; Kumar, Vinod; Zwergel, Clemens
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology
2022 Barone, S.; Cassese, E.; Alfano, A. I.; Brindisi, M.; Summa, V.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation
2021 Relitti, N.; Saraswati, A. P.; Chemi, G.; Brindisi, M.; Brogi, S.; Herp, D.; Schmidtkunz, K.; Saccoccia, F.; Ruberti, G.; Ulivieri, C.; Vanni, F.; Sarno, F.; Altucci, L.; Lamponi, S.; Jung, M.; Gemma, S.; Butini, S.; Campiani, G.
Flow synthesis approaches to privileged scaffolds - recent routes reviewed for green and sustainable aspects
2021 Alfano, A. I.; Brindisi, M.; Lange, H.
Coupling Interrupted Fischer and Multicomponent Joullié-Ugi to Chase Chemical Diversity: from Batch to Sustainable Flow Synthesis of Peptidomimetics
2021 Alfano, A. I.; Buommino, E.; Ferraro, M. G.; Irace, C.; Zampella, A.; Lange, H.; Brindisi, M.
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation
2020 Saraswati, A Prasanth; Relitti, Nicola; Brindisi, Margherita; Osko, Jeremy D; Chemi, Giulia; Federico, Stefano; Grillo, Alessandro; Brogi, Simone; Mccabe, Niamh H; Turkington, Richard C; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania; Ghanim, Magda; Kelly, Vincent P; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra; Butini, Stefania; Christianson, David W; Campiani, Giuseppe
Telomerase-based cancer therapeutics: A review on their clinical trials
2020 Relitti, N.; Saraswati, A. P.; Federico, S.; Khan, T.; Brindisi, M.; Zisterer, D.; Brogi, S.; Gemma, S.; Butini, S.; Campiani, G.
Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry
2020 Ghosh, A. K.; Brindisi, M.
Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents
2020 Saccoccia, Fulvio; Brindisi, Margherita; Gimmelli, Roberto; Relitti, Nicola; Guidi, Alessandra; Saraswati, A. Prasanth; Cavella, Caterina; Brogi, Simone; Chemi, Giulia; Butini, Stefania; Papoff, Giuliana; Senger, Johanna; Herp, Daniel; Jung, Manfred; Campiani, Giuseppe; Gemma, Sandra; Ruberti, Giovina
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases
2020 Brindisi, Margherita; Saraswati, A Prasanth; Brogi, Simone; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe
Targeting Endocannabinoid Metabolism: an Arrow with Multiple Tips Against Multiple Sclerosis
2020 Maramai, S.; Brindisi, M.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7
2020 Gutschow, M.; Eynde, J. J. V.; Jampilek, J.; Kang, C.; Mangoni, A. A.; Fossa, P.; Karaman, R.; Trabocchi, A.; Scott, P. J. H.; Reynisson, J.; Rapposelli, S.; Galdiero, S.; Winum, J. -Y.; Brullo, C.; Prokai-Tatrai, K.; Sharma, A. K.; Schapira, M.; Azuma, Y. -T.; Cerchia, L.; Spete, M.; Torri, G.; Collina, S.; Geronikaki, A.; Garcia-Sosa, A. T.; Helena Vasconcelos, M.; Sousa, M. E.; Kosalec, I.; Tuccinardi, T.; Duarte, I. F.; Salvador, J. A. R.; Bertinaria, M.; Pellecchia, M.; Amato, J.; Rastelli, G.; Gomes, P. A. C.; Guedes, R. C.; Sabatier, J. -M.; Estevez-Braun, A.; Pagano, B.; Mangani, S.; Ragno, R.; Kokotos, G.; Brindisi, M.; Gonzalez, F. V.; Borges, F.; Miloso, M.; Rautio, J.; Munoz-Torrero, D.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination | 1.1 Articolo in rivista | 2023 | Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo | |
| Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds | 1.1 Articolo in rivista | 2023 | Alfano, Antonella Ilenia; Pelliccia, Sveva; Rossino, Giacomo; Chianese, Orazio; Summa, Vincenzo; Collina, Simona; Brindisi, Margherita | |
| Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds | 1.1 Articolo in rivista | 2023 | Alfano, A. I.; Pelliccia, S.; Rossino, G.; Chianese, O.; Summa, V.; Collina, S.; Brindisi, M. | |
| Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation | 1.1 Articolo in rivista | 2023 | Pelliccia, Sveva; Alfano, Antonella Ilenia; Gomes Da Assunção, Beatriz Ramos; Turco, Luigia; Lembo, Francesca; Summa, Vincenzo; Buommino, Elisabetta; Brindisi, Margherita | |
| Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route | 1.1 Articolo in rivista | 2022 | Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo | |
| Amide Bonds Meet Flow Chemistry: A Journey into Methodologies and Sustainable Evolution | 1.1 Articolo in rivista | 2022 | Alfano, A. L.; Lange, H.; Brindisi, M. | |
| Mechanochemical Fischer indolisation: an eco-friendly design for a timeless reaction | 1.1 Articolo in rivista | 2022 | Porcheddu, A.; Mocci, R.; Brindisi, M.; Cuccu, F.; Fattuoni, C.; Delogu, F.; Colacino, E.; D'Auria, M. V. | |
| Efficacy of selective histone deacetylase 6 inhibition in mouse models of Pseudomonas aeruginosa infection: A new glimpse for reducing inflammation and infection in cystic fibrosis | 1.1 Articolo in rivista | 2022 | Brindisi, Margherita; Barone, Simona; Rossi, Alice; Cassese, Emilia; Del Gaudio, Nunzio; Feliz Morel, Álvaro Javier; Filocamo, Gessica; Alberico, Alessia; De Fino, Ida; Gugliandolo, Davide; Babaei, Mehrad; Bove, Guglielmo; Croce, Martina; Montesano, Camilla; Altucci, Lucia; Bragonzi, Alessandra; Summa, Vincenzo | |
| Editorial: Multi-target directed ligands for the treatment of cancer | 1.1 Articolo in rivista | 2022 | Brindisi, Margherita; Kessler, Sonja M; Kumar, Vinod; Zwergel, Clemens | |
| Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology | 1.1 Articolo in rivista | 2022 | Barone, S.; Cassese, E.; Alfano, A. I.; Brindisi, M.; Summa, V. | |
| Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation | 1.1 Articolo in rivista | 2021 | Relitti, N.; Saraswati, A. P.; Chemi, G.; Brindisi, M.; Brogi, S.; Herp, D.; Schmidtkunz, K.; Saccoccia, F.; Ruberti, G.; Ulivieri, C.; Vanni, F.; Sarno, F.; Altucci, L.; Lamponi, S.; Jung, M.; Gemma, S.; Butini, S.; Campiani, G. | |
| Flow synthesis approaches to privileged scaffolds - recent routes reviewed for green and sustainable aspects | 1.8 Articolo in rassegna (review) | 2021 | Alfano, A. I.; Brindisi, M.; Lange, H. | |
| Coupling Interrupted Fischer and Multicomponent Joullié-Ugi to Chase Chemical Diversity: from Batch to Sustainable Flow Synthesis of Peptidomimetics | 1.1 Articolo in rivista | 2021 | Alfano, A. I.; Buommino, E.; Ferraro, M. G.; Irace, C.; Zampella, A.; Lange, H.; Brindisi, M. | |
| Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation | 1.1 Articolo in rivista | 2020 | Saraswati, A Prasanth; Relitti, Nicola; Brindisi, Margherita; Osko, Jeremy D; Chemi, Giulia; Federico, Stefano; Grillo, Alessandro; Brogi, Simone; Mccabe, Niamh H; Turkington, Richard C; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania; Ghanim, Magda; Kelly, Vincent P; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra; Butini, Stefania; Christianson, David W; Campiani, Giuseppe | |
| Telomerase-based cancer therapeutics: A review on their clinical trials | 1.8 Articolo in rassegna (review) | 2020 | Relitti, N.; Saraswati, A. P.; Federico, S.; Khan, T.; Brindisi, M.; Zisterer, D.; Brogi, S.; Gemma, S.; Butini, S.; Campiani, G. | |
| Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry | 1.1 Articolo in rivista | 2020 | Ghosh, A. K.; Brindisi, M. | |
| Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents | 1.1 Articolo in rivista | 2020 | Saccoccia, Fulvio; Brindisi, Margherita; Gimmelli, Roberto; Relitti, Nicola; Guidi, Alessandra; Saraswati, A. Prasanth; Cavella, Caterina; Brogi, Simone; Chemi, Giulia; Butini, Stefania; Papoff, Giuliana; Senger, Johanna; Herp, Daniel; Jung, Manfred; Campiani, Giuseppe; Gemma, Sandra; Ruberti, Giovina | |
| Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases | 1.1 Articolo in rivista | 2020 | Brindisi, Margherita; Saraswati, A Prasanth; Brogi, Simone; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe | |
| Targeting Endocannabinoid Metabolism: an Arrow with Multiple Tips Against Multiple Sclerosis | 1.1 Articolo in rivista | 2020 | Maramai, S.; Brindisi, M. | |
| Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7 | 1.2 Recensione in rivista | 2020 | Gutschow, M.; Eynde, J. J. V.; Jampilek, J.; Kang, C.; Mangoni, A. A.; Fossa, P.; Karaman, R.; Trabocchi, A.; Scott, P. J. H.; Reynisson, J.; Rapposelli, S.; Galdiero, S.; Winum, J. -Y.; Brullo, C.; Prokai-Tatrai, K.; Sharma, A. K.; Schapira, M.; Azuma, Y. -T.; Cerchia, L.; Spete, M.; Torri, G.; Collina, S.; Geronikaki, A.; Garcia-Sosa, A. T.; Helena Vasconcelos, M.; Sousa, M. E.; Kosalec, I.; Tuccinardi, T.; Duarte, I. F.; Salvador, J. A. R.; Bertinaria, M.; Pellecchia, M.; Amato, J.; Rastelli, G.; Gomes, P. A. C.; Guedes, R. C.; Sabatier, J. -M.; Estevez-Braun, A.; Pagano, B.; Mangani, S.; Ragno, R.; Kokotos, G.; Brindisi, M.; Gonzalez, F. V.; Borges, F.; Miloso, M.; Rautio, J.; Munoz-Torrero, D. |
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