The benefit of balloon angioplasty, with or without stenting, for the treatment of patients with renal artery stenosis remains controversial. A number of randomized controlled trials have attempted to determine its efficacy but the matter remains unclear. A 2014 Cochrane Review, which combined data from eight trials, showed homogeneity amongst the trials with no significant benefit shown. This systematic review replicates the same research methods and meta-analysis while expanding it to include papers between 2014 and 2018. One of the trials included in the previous review published results in the interim. Additionally, two ongoing trials identified in the 2014 review are yet to publish any result. Meta-analysis of the reports showed no heterogeneity between trials and no significant improvement shown by balloon angioplasty, with or without stenting, versus medical therapy. Further studies are recommended in order to assess the benefits of balloon angioplasty for patients with more severe renal artery stenosis.
Endovascular Treatment Versus Medical Therapy for Hypertensive Patients with Renal Artery Stenosis: An Updated Systematic Review / Piaggio, Davide; Bracale, Umberto; Pecchia, Leandro; Di Taranto, Maria Donata; Sodo, Maurizio; Bracale, Umberto Marcello. - In: ANNALS OF VASCULAR SURGERY. - ISSN 0890-5096. - 61:(2019), pp. 445-454. [10.1016/j.avsg.2019.04.050]
Endovascular Treatment Versus Medical Therapy for Hypertensive Patients with Renal Artery Stenosis: An Updated Systematic Review
Bracale, Umberto;Pecchia, Leandro;Di Taranto, Maria Donata;Sodo, Maurizio;Bracale, Umberto Marcello
2019
Abstract
The benefit of balloon angioplasty, with or without stenting, for the treatment of patients with renal artery stenosis remains controversial. A number of randomized controlled trials have attempted to determine its efficacy but the matter remains unclear. A 2014 Cochrane Review, which combined data from eight trials, showed homogeneity amongst the trials with no significant benefit shown. This systematic review replicates the same research methods and meta-analysis while expanding it to include papers between 2014 and 2018. One of the trials included in the previous review published results in the interim. Additionally, two ongoing trials identified in the 2014 review are yet to publish any result. Meta-analysis of the reports showed no heterogeneity between trials and no significant improvement shown by balloon angioplasty, with or without stenting, versus medical therapy. Further studies are recommended in order to assess the benefits of balloon angioplasty for patients with more severe renal artery stenosis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
