TRP (Transient Receptor Potential) channels and CB (cannabinoid) receptors are deputed to the regulation of sensory, homeostatic, and inflammatory events in human organism. Therefore, their modulation promises to have relevant applications in important therapeutic areas as inflammation, pain, and cancer. This review summarizes the contribution of marine research in this relatively young field, highlighting the potential of the chemodiversity carried by marine natural products in the discovery of new ligands.
Marine metabolites modulating CB receptors and TRP channels / Rigano, Daniela; Formisano, Carmen; TAGLIALATELA SCAFATI, Orazio. - In: PLANTA MEDICA. - ISSN 0032-0943. - 82:(2016), pp. 761-766. [10.1055/s-0042-101352]
Marine metabolites modulating CB receptors and TRP channels
RIGANO, DANIELAPrimo
;FORMISANO, CARMEN;TAGLIALATELA SCAFATI, ORAZIO
Ultimo
2016
Abstract
TRP (Transient Receptor Potential) channels and CB (cannabinoid) receptors are deputed to the regulation of sensory, homeostatic, and inflammatory events in human organism. Therefore, their modulation promises to have relevant applications in important therapeutic areas as inflammation, pain, and cancer. This review summarizes the contribution of marine research in this relatively young field, highlighting the potential of the chemodiversity carried by marine natural products in the discovery of new ligands.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.