Rasmussen's encephalitis (RE) is an immune-mediated disease, typically affecting a single cerebral hemisphere. Intractable epilepsy, hemiplegia and cognitive decline represent the clinical features; movement disorders have rarely been described. We report a case of adult-onset RE which developed hemiparkinsonism after an extraordinarily long prodromal period; to date, this is the first description of parkinsonism in RE. The association between cortical symptoms and extrapyramidal features evokes a clinical suspect of corticobasal syndrome (CBS); our patient satisfies the diagnostic criteria for possible CBS. Clinical and neuro-radiological reasons might further explain why RE accompanied by extrapyramidal signs may present as a CBS.

Parkinsonism in adult-onset Rasmussens's encephalitis: a clinical picture presenting as corticobasal syndrome / Bilo, Leonilda; Peluso, Silvio; Antenora, Antonella; DE ROSA, Anna; Esposito, Marcello; Barbato, Stefano; Pappata', Sabina; DE MICHELE, Giuseppe. - In: INTERNATIONAL JOURNAL OF NEUROSCIENCE. - ISSN 0020-7454. - 126:12(2016), pp. 1136-1138. [10.3109/00207454.2015.1135438]

Parkinsonism in adult-onset Rasmussens's encephalitis: a clinical picture presenting as corticobasal syndrome

BILO, LEONILDA;PELUSO, SILVIO;ANTENORA, ANTONELLA;DE ROSA, ANNA;ESPOSITO, MARCELLO;BARBATO, STEFANO;PAPPATA', Sabina;DE MICHELE, GIUSEPPE
2016

Abstract

Rasmussen's encephalitis (RE) is an immune-mediated disease, typically affecting a single cerebral hemisphere. Intractable epilepsy, hemiplegia and cognitive decline represent the clinical features; movement disorders have rarely been described. We report a case of adult-onset RE which developed hemiparkinsonism after an extraordinarily long prodromal period; to date, this is the first description of parkinsonism in RE. The association between cortical symptoms and extrapyramidal features evokes a clinical suspect of corticobasal syndrome (CBS); our patient satisfies the diagnostic criteria for possible CBS. Clinical and neuro-radiological reasons might further explain why RE accompanied by extrapyramidal signs may present as a CBS.
2016
Parkinsonism in adult-onset Rasmussens's encephalitis: a clinical picture presenting as corticobasal syndrome / Bilo, Leonilda; Peluso, Silvio; Antenora, Antonella; DE ROSA, Anna; Esposito, Marcello; Barbato, Stefano; Pappata', Sabina; DE MICHELE, Giuseppe. - In: INTERNATIONAL JOURNAL OF NEUROSCIENCE. - ISSN 0020-7454. - 126:12(2016), pp. 1136-1138. [10.3109/00207454.2015.1135438]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/625902
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